PMN cell counts and phagocytic activity of highly trained athletes depend on training period
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Deutscher übersetzter Titel: | Die Zahl der polymorphkernigen Leukozyten und die Phagozytose-Aktivitaet bei Hochleistungssportlern haengt von der Trainingsphase ab |
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Autor: | Hack, V.; Strobel, G.; Weiß, M.; Weicker, H. |
Erschienen in: | Journal of applied physiology |
Veröffentlicht: | 77 (1994), 4, S. 1731-1735, Lit. |
Format: | Literatur (SPOLIT) |
Publikationstyp: | Zeitschriftenartikel |
Medienart: | Gedruckte Ressource |
Sprache: | Englisch |
ISSN: | 8750-7587, 0021-8987, 0161-7567, 1522-1601 |
Schlagworte: | |
Online Zugang: | |
Erfassungsnummer: | PU199502074888 |
Quelle: | BISp |
TY - JOUR AU - Hack, V. A2 - Hack, V. A2 - Strobel, G. A2 - Weiß, M. A2 - Weicker, H. DB - BISp DP - BISp KW - Differentialblutbild KW - Granulozyt, neutrophiler KW - Hochleistungssport KW - Immunologie KW - Immunsystem KW - Leistungssportler KW - Leukozytenzahl KW - Phagozytose KW - Sportmedizin KW - Trainingsintensität KW - Trainingsperiode KW - Übertraining LA - eng TI - PMN cell counts and phagocytic activity of highly trained athletes depend on training period TT - Die Zahl der polymorphkernigen Leukozyten und die Phagozytose-Aktivitaet bei Hochleistungssportlern haengt von der Trainingsphase ab PY - 1994 N2 - We tested the hypothesis that polymorphonuclear leukocyte (PMN) cell counts and phagocytic activity determined by latex ingestion and superoxide anion production are influenced by different training periods. We investigated long-distance runners before and up to 24 h after a graded exercise test to exhaustion during moderate training (MT) and intense training (IT) and compared them with untrained (control) subjects. Cell counts and phagocytic activity at rest and after exercise did not differ significantly between MT and control. On the contrary, IT showed a significant (P = 0.05) decrease in PMN cell count at rest (2.55 +/- 0.3 cells/nl) compared with MT (3.63 +/- 0.2 cells/nl) and control (3.41 +/- 0.8 cells/nl). Furthermore, phagocytic activity was significantly reduced (P = 0.05) in IT at rest and after exercise compared with MT and control. A strong inverse correlation (r = -0.75; P= 0.01) between epinephrine and superoxide anion production was found. These results provide evidence that the phagocytic activity depends on the training period and indicate impaired PMN functions during IT, which might lead to increased susceptibility to infection. Verf.-Referat SP - S. 1731-1735 SN - 8750-7587 JO - Journal of applied physiology IS - 4 VL - 77 M3 - Gedruckte Ressource ID - PU199502074888 ER -