Immunological status of competitive cyclists before and after the training season

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Bibliographic Details
Title translated into German:Immunstatus von Radrennsportlern vor und nach einer Trainingssaison
Author:Baj, Z.; Kantorski, J.; Majewska, E.; Zeman, K.; Pokoca, L.; Fornalczyk, E.; Tchorzewski, H.; Sulowska, Z.; Lewicki, R.
Published in:International journal of sports medicine
Published:15 (1994), 6 , S. 319-324, Lit.
Format: Publications (Database SPOLIT)
Publication Type: Journal article
Media type: Print resource
ISSN:0172-4622, 1439-3964
Online Access:
Identification number:PU199511103519

Author's abstract

The total number of leucocytes, T lymphocyte subsets, mitogen induced proliferation of lymphocytes, IL-2 generation, adherence capacity and chemiluminescence of granulocytes were measured and a leukergy test performed in fifteen young cyclists. The investigations were carried out at rest at the beginning of a training season and after six months of intensive training and a racing season, cycling approximately 500 km a week. Baseline values of the tested immune parameters were within the range observed in 16 non-trained healthy controls except significantly increased non stimulated neutrophil chemiluminescence. The second cyclo-ergometer test in August showed a marked improvement in the performance capacity of the cyclists. Significant decrease in absolute numbers of CD3+ and CD4+ cells, diminished IL-2 generation and fMLP and PMA stimulated chemiluminescence of neutrophils were noted. Surprisingly, a marked increase in lymphocyte proliferation induced by PHA and anti-CD3 MoAb and normalisation in non stimulated neutrophil chemiluminescence were also abserved at rest after the training season. We conclude that long-lasting intensive training may result in significant alterations in lymphocyte number and composition and in neutrophil oxidative burst capacity, but their actual significance for immunity is seen controversially. Verf.-Referat