Abstract

Doping ist vor allem in der Zeit der Olympischen Sommerspiele sowie während der Tour de France Rundfahrt ein immer wiederkehrendes und kontrovers diskutiertes Thema. Mit diesem Sammelband, der alle Tagungsberichte des 16. Kölner Workshops (Manfred Donike Workshop) enthält, werden die aktuellen Fortschritte von Dopinganalysen vorgestellt. Mit neueren Analysenmethoden und wissenschaftlichen Erkenntnisse versuchen die Dopingkontrolleure und -fahnder das „Katz- und Mausspiel“ für sich zu entscheiden. Die Autoren und ihre Beiträge sind: I. Anabolic Agents. 1. D. Thieme, J. Grosse, H. Sachs, R.K. Mueller: Detection of several anabolic steroids of abuse in human hair; 2. M. Machnik, H. Geyer, S. Horning, A. Breidbach, P. Delahaut, W. Schänzer: Longterm detection of clenbuterol in human scalp hair by means of gaschromatography / high resolution mass sectrometry (GC/HRMS); 3. W. Schänzer, H. Geyer, S. Horning: 17,17-dimethyl-18-nor-5beta-androst-1,13-dien-3alpha-ol (18-normetenol) in longterm detection and confirmation of positive metandienone cases; 4. K. Chrostowski, D. Kwiatkowska, E. Partyka, B. Wójcikowska-Wójcik: Danazol detection in doping analysis in urine; 5. Yinong Zhang, Moutian Wu, Xin Liu, Changjiu Zhang: Analysis of urinary metabolites of mibolerone in man by gas chromatography / tandem mass spectrometry; 6. S. Rendic, E. Nolteernsting, W. Schänzer: Metabolism of anabolic steroids by recombinant human cytochrome P450 enzymes. II. Detection of 19-Norandrosterone; 7. M. Ciardi, R. Ciccoli, M.V. Barbarulo, R. Nicoletti: Presence of norandrosterone in "normal" urine samples; 8. P. Van Eenoo, F.T. Delbeke, F.H. De Jong, P. De Backer: Urinary metabolites of endogenous nandrolone in women: A case study; 9. U. Mareck-Engelke, H. Geyer, W.Schänzer: 19-norandrosterone - criteria for the decision making process; 10. N. Robinson, C. Cardis, A. Dienes, C. Schweizer, M. Saugy, L. Rivier: Immunoaffinity chromatography combined with the ion trap technique in order to detect traces of 19-norandrosterone. III. Steroid Profiling. 11. M. Ueki, M. Okano, A. Ikekita: Nagano strategy against natural hormone doping - testosterone, DHT, androstenedione and DHEA -;12. V.P. Uralets, P.A. Gillette, R.K. Latven: Over-the-counter anabolic steroids 4-androsten-3,17-dione; 4-androsten-3beta,17beta-diol, and 19-nor-4-androsten-3,17-dione: excretion studies in men; 13. P. Van Eenoo, F.T. Delbeke, N. Desmet, P. De Backer: Excretion studies with 4-androstene-3,17-dione; 14. M. Garle, E. Palonek: Androstenedione: excretion studies from single and multiple dose Experiments; 15. S.H. Peng, J. Segura, M. Farré, J.C. González, X. De La Torre: Overall biological markers of oral testosterone undecanoate misuse; 16. C. Schweizer, C. Cardis, M. Cauderay, L. Rivier, M. Saugy: Profile variations through puberty in young adolescent girls; 17. R. De La Torre, X. De La Torre, J. Segura, M.T. Smeyers, R. Ventura, J.M. Torres, C. Alía, T. Baró: Urine contamination by micro-organisms and alterations in the endogenous steroid profile. A prospective study; 18. R. Grucza, J. Smorawinski, K. Chrostowski: Ketoconazole test - A case study. IV. Techniques of MS Detection. 19. U. Flenker, S. Horning, E. Nolteernsting, H. Geyer, W. Schänzer: Measurement of 12C/13C-ratios to confirm misuse of endogenous Steroids; 20. Xin Liu, Moutian Wu, Yinong Zhang, Changjiu Zhang: Application of TSQ-7000 in doping control analysis; 21. G. Trout; J. Murby, R. Kazlauskas: High resolution mass spectrometry in the antipodes; 22. S. Horning, M. Hoehn, H. Muenster, H. Geyer, W. Schaenzer: GC/HRMS-ION TRAP Screening and confirmation of anabolic steroids; 23. R. Ciccoli, F. Rosati, F. Rossi, R. Nicoletti: One Year Use of AUTOSPEC-TOF: Experience of antidoping lab in Rome. V. Peptide Hormones. 24. A. Breidbach, W. Schänzer: Individual reference ranges for serum erythropoietin (sEPO) - A possible approach to detect misuse; 25. P. Hemmersbach, J. Stray-Gundersen, J. Hallén, E. Haug, R. Bahr, K.I. Birkeland: The effects of supraphysiological doses of erythropoietin in healthy young men; 26. V. Skibeli, G. Nissen-Lie, A. Noreau, P. Torjesen, P. Hemmersbach, K.I. Birkeland: Immuno-affinity extraction of erythropoietin from human serum by magnetic beads; 27. A. Leinonen, R. Tähtelä, E. Karjalainen: Detection of human chorionic gonadotropin in urine by two different Immunoassays. VI. Stimulating Substances. 28. V.A. Semenov, S.L. Bolotov, V.F. Sizoi: New stimulant of Russia carphedon; 29. J. Grosse, D. Thieme, R. Lang, R.K. Mueller: Elucidation of carphedon doping - designer psychostimulant in sports; 30. D.H. Van De Kerkhof, D. De Boer, R.A.A. Maes: The Position of the Hydroxy Group in the Main Bromantane Metabolite; 31. Kairong Cui, Moutian Wu, Xin Liu, Yinong Zhang, Shan Wang: Study on the metabolites of bromantane in urine using GC/MS and GC/tandem MS/MS; 32. D. Goudreault, C. Ayotte: The identification of fenozolone urinary metabolites. VII. New Aspects. 33. R. Bergés, J. Segura, R. Ventura, X. De La Torre, M. Mas, M. Farré, K.D. Fitch, A.R. Morton, M. Ueki: Oral versus inhaled salbutamol: is distinction possible by urine analysis?; 34. H. Geyer, U. Mareck-Engelke, W. Schänzer: The black market of anabolic agents; 35. R. Kazlauskas, A. Lisi, G. Trout: Chiral derivatisation; 36. K. Chrostowski, D. Kwiatkowska, A. Pokrywka, K. Bal: Aminoglutethimide detection in urine samples; 37. P.J. Van Der Merwe, J. Pretorius, E. Kruger: The influence of antimalarial drugs on dope testing. VIII. Poster Presentation. 38. N. Halatcheva, A. Tsoutsoulova-Draganova, D. Carova: Analyses of urine samples of the first Bulgarian "Methadone Baby"; 39. A. Tsoutsoulova-Draganova, N. Halatcheva, V. Kurteva, D. Carova, A. Andreeva, M. Anguelova: Investigations on a "black market's drug - carphedon"; 40. G. Sigmund, I. Seinsch, W. Schänzer: Detection of phentermine and phentermine derivatives as metabolites of Oxethazine; 41. I. Bellahn, E. Nolteernsting, G. Opfermann, W. Schänzer: Preliminary results of excretion studies with salbutamol. Inhaltsverzeichnis