Abstract

Das Buch fasst die Proceedings des 20. Kölner Workshops (Manfred Donike Workshop) aus dem Jahr 2002 zusammen. Es werden neue Testverfahren und Untersuchungsmethoden der Dopinganalytik vorgestellt und evaluiert. Der Schwerpunkt liegt dabei auf Verfahren, mit denen verschiedene klassische oder neu entwickelte anabole androgene Steroide sowie exogenes Erythropoetin nachgewiesen werden können. Die Autoren und ihre Beiträge sind: I. LECTURES. 1. C. AYOTTE, C. GUAY, M. CLÉROUX, D. GOUDREAULT, A. FAKIRIAN: The origin of elevated levels of norandrosterone in human urine: half-truths vs facts; 2. S. JÅTHUN, H. S. LUND, P. FEDORCSÀK, R. STORENG, P. TORJESEN, P. HEMMERSBACH: Synthesis of nandrolone in the human ovary;3. U. MARECK-ENGELKE, G. SIGMUND, G. OPFERMANN, H. GEYER, W. SCHÄNZER: Identification of the aromatase inhibitor aminoglutethimide in doping Analysis; 4. T. BASSINDALE, D.A. COWAN, S. DALE, A.J. HUTT, A.T. KICMAN: Disposition of androstenedione and testosterone following oral administration of androstenedione to healthy female volunteers; influence on the urinary T/E ratio; 5. P. VAN EENOO, F.T. DELBEKE, N. DESMET: Exretion studies with a supplement containing 5 alpha-androst-1-en, 17beta-diol; 6. V.P. URALETS, P.A. GILLETTE: 5alpha-androstan-3,17beta-diol and 1,4-androstadien-3,17-dione, new anabolic steroids available on the internet as nutritional supplements. metabolism and detection in urine; 7. H. GEYER, M.K. PARR, U. REINHART, Y. SCHRADER, U. MARECK-ENGELKE, W. SCHÄNZER: Analysis of non-hormonal nutritional supplements for anabolic androgenic steroids - an international study; 8. M.K. PARR, H. GEYER, U. REINHART, W. SCHÄNZER: Approaches towards an improved analysis of nutritional supplements for anabolic androgenic steroids; 9. M. THEVIS, G. OPFERMANN, W. SCHÄNZER: Mass spectrometric behaviour of diuretics after electrospray ionisation and collision-induced dissociation; 10. T. KUURANNE, A. LEINONEN, K. KUOPPASALMI, S. PEDERSEN-BJERGAARD, K. RASMUSSEN, T. KOTIAHO, R. KOSTIAINEN: Liquid-phase microextraction (LPME) as a sample purification method in LC-MS/MS Analysis of Anabolic Steroid Glucuronides; 11. L. AMENDOLA, C. COLAMONICI, F. GARRIBBA, F. BOTRÈ: Microwave-assisted derivatization: application to the analysis of diuretics and corticosteroids; 12. R. KAZLAUSKAS, D. COWAN: WAADS QA Programme 2001/2002; 13. R. VENTURA, C. JIMÉNEZ, J. SEGURA, R. DE LA TORRE AND THE MEMBERS OF THE CONSORTIUM OF ALADIN 2002: R. DE LA TORRE, R. VENTURA, W. SCHÄNZER, D. COWAN, P. HEMMERSBACH, J. WILLIAMS, R. KAZLAUSKAS. D. CATLIN: Stability studies of selected doping agents in urine samples (i): caffeine and ephedrine derivatives; 14. J.A. PASCUAL, F. LASNE, C. HOWE, M. SAUGY, P. HEMMERSBACH, V. BELALCAZAR, L. MARTIN, J. GRAINGER Y. PFISTER, P. MANGIN, G. NISSEN-LIE, V. SKIBELI: project for inter-laboratory comparison of the method for the detection of rhEPO in human urine. results, conclusions and current status; 15. G. NISSEN-LIE, P. HEMMERSBACH, E. HAUG E, G. TJØNNFJORD, P. TORJESEN, V. SKIBELI: Charge analyses of human erythropoietin and analogues; 16. N. ROBINSON, Y. PFISTER, P. MANGIN, M. SAUGY: One year's experiment with the blood screening test to fight against rhEPO doping; 17. C. ALMA, G.J. TROUT: Detection of haemoglobin based oxygen carriers; 18. A. GOTZMANN, S. VOSS, M. MACHNIK, W. SCHÄNZER: Detection of hemopure® and hemoglobin in human plasma by HPLC/UV and different types of columns - an approach to screen for this substance in doping analysis; 19. M. THEVIS, S. GUDDAT, W. SCHÄNZER: Determination of HES, dextran and mannitol in human urine. II. POSTER PRESENTATION. 1. A. KRESS, MARECK-ENGELKE, U., GEYER, H., W. SCHÄNZER: Alternative bulk materials to XAD-2 (serdolit® AD-II, serva); 2. C. VON KUK, W. SCHÄNZER: Estrogens as additional parameters of steroidprofile in doping analysis; 3. C. R. CARDOSO, M. A. S. MARQUES, I. B. TALHAS, R. C. CAMINHA, F. R. AQUINO NETO: Determination of oxymetholone in human plasma and saliva by high resolution gas chromatography -mass spectrometry; 4. D. LONGO, C. COLAMONICI, F. MOLAIONI, F. BOTRÈ: Synephrine (oxedrine): analytical and pharmacological issues; 5. S. KERKENI, S. BOUABDALLAH, H. TRABELSI, K. BOUZOUITA: Brief report on the doping control during the XIVèmes Mediterranean Games in Tunis from 2nd to 15th of September 2001; 6. A. WINGENDER, G. SIGMUND, W. SCHÄNZER: Local anaesthetics in sport; 7. S.-H. PENG, C. DE BOLÒS, J. SEGURA, J.A. PASCUAL: Capillary electrophoresis behaviour of recombinant human erythropoietin; 8. G. NISSEN-LIE, K. BIRKELAND, P. HEMMERSBACH, E. HAUG, V. SKIBELI: Urinary charge patterns of recombinant human erythropoietin during controlled administration in athletes; 9. J. GRINYER, B. HERBERT, N. PACKER, C. HOWE AND, G.J. TROUT: Development of an immobilised ph gradient gel for the EPO urine test; 10. P. J. VAN DER MERWE, E. GROBBELAAR, D. YEOWART: Stability of 19-norandrosterone and 19-noretiocholanolone glucuronide in urine under various storage conditions; 11. G.J. TROUT , S. SOO, K. KELLY: Longitudinal variability of T/E ratios in Australian athletes; 12. G. E. VÂJIALA, M. LAMOR, R. SUBASU: The tracing out of the contamination with doping agents of the nutritional Supplements; 13. K. AARSKOG, H. S. LUND, C. HELLE, P. HEMMERSBACH: Nutritional supplements - A risk assessment; 14. H. M. G. PEREIRA, M. A. S. MARQUES, F. R. AQUINO NETO: Initial study of incidental contamination of clostebol in athletes by sexual Intercourse. Inhaltsverzeichnis