Abstract

Das Buch fasst die Proceedings des 19. Kölner Workshops (Manfred Donike Workshop) aus dem Jahr 2001 zusammen. Es werden Studien zu verschiedenen Substanzen (insbesondere zu verschiedenen Steroiden) vorgestellt, mit denen Dopingmissbrauch betrieben wird bzw. betrieben werden könnte. Der Schwerpunkt liegt dabei auf der Darstellung der entsprechenden Testverfahren, mit denen diese Stoffe analysiert und nachgewiesen werden können. Die Autoren und ihre Beiträge sind: I. Lectures: 1. M.THEVIS, G.OPFERMANN, W.SCHÄNZER: Screening and Confirmation Methods for the Detection of Plasma Volume Expanders in Human Urine; 2. D. DE BOER, H. VENEMA, A. CASTAÑERA AJENJO, L.J.A.L.DOS REYS, R.A.A. MAES: Profiling Cannabinoids; the Significance of the Detection of 11-Nor-delta9-Tetrahydrocannabivarin-9-carboxylic Acid; 3. M.K. HENZE, H. SPAHN-LANGGUTH, W. SCHÄNZER: Reactions of Salbutamol and Reproterol with Urine Matrix Components - Preliminary Results; 4. M. THEVIS, W. SCHÄNZER: High Speed Determination of ß-Blockers in Human Urine by LC/MS/MS 5. G. GMEINER, T. GEISENDORFER, J. KAINZBAUER, M. NIKOLAJEVIC: Quantification of Ephedrines in Urine without Sample Preparation; 6. U. MARECK-ENGELKE, G. SIGMUND, G.OPFERMANN, H. GEYER, W. SCHÄNZER: Screening for Tamoxifen, Clomiphene and Cyclofenil in Doping Analysis; 7. H. GEYER, U. MARECK-ENGELKE, A. WAGNER, W. SCHÄNZER: The Analysis of "Non-Hormonal" Nutritional Supplements for Prohormones; 8. D. GOUDREAULT, P. BHÉRER, J.-F. LÉVESQUE, D. POIRIER, C. AYOTTE: Androstenedione Metabolism: End of the Story &; 9. V.P. URALETS , P.A. GILLETTE: Individual Variations of Urinary Steroid Profiles in Glucuronide and Sulfate Fractions after DHEA Oral Administration; 10. P. VAN EENOO, F.T. DELBEKE, N. DESMET, P. DE BACKER: Excretion Studies with 7-Keto-Dehydroepiandrosterone; 11. J. MARCOS, J.A. PASCUAL, X. DE LA TORRE, J. SEGURA: Fast and Comprehensive Screening of Anabolic Agents and other Compounds in Human Urine by GC/MS/MS; 12. M.THEVIS, G.OPFERMANN, W.SCHÄNZER: Synthesis and GC/MS-Characterization of Glucuronide Conjugates of Anabolic Steroids (2); 13. V. P. URALETS, P.A. GILLETTE: Enhanced Steroid Screening achieved by fast GC/MS with Hydrogen Carrier Gas; 14. M. MACHNIK, Y. SCHRADER, W. SCHÄNZER: Plasma Levels of 19-Norsteroids after Oral and Buccal Administration of Norandrostenedione; 15. C. AYOTTE, D. GOUDREAULT, A. LAJEUNESSE, M. CLÉROUX, Y.RICHARD, A. CHARLEBOIS, J.-P. COUTURE, A. FAKIRIAN: GC/C/IRMS and GC/MS in "Natural" Steroids Testing; 16. M. UEKI, Y. TAKAO, M. OKANO, A. IKEKITA, M. SATO: Differentiation of Endogenous and Exogenous Steroids in Urine by Means of Isotope Ratio Mass Spectrometry; 17. C. WA, M. WU, Y. ZHANG, X. LIU, C. ZHANG: Distinguish Endogenous and Exogenous Epitestosterone Using GC/C/IRMS with TLC Purification; 18. R. KAZLAUSKAS: Sydney Olympics 2000: An Overview; 19. U. FLENKER, W. SCHÄNZER: Kinetic Isotope Effects during Metabolism of delta4-Steroids; 20. U. FLENKER, W. SCHÄNZER: 13C/12C- Ratios in Caffeine from Different Sources and in Urinary Excreted Caffeine; 21. G.J. TROUT, K.R. EMSLIE, C. HOWE, R. KAZLAUSKAS, F. LASNE: An Overview of Testing for EPO at the Sydney 2000 Olympic Games and Beyond. II. POSTER PRESENTATION 1. H. M. G. PEREIRA. M. A. S. MARQUES, J. N. CARDOSO, F. R. AQUINO NETO: Derivatization Study on Endogenous and Synthetic Corticosteroids by Gas Chromatography Mass Spectrometry; 2. B. YAP, R. KAZLAUSKAS: Rapid HPLC Screening of Chlorothiazide, Torasemide, Xipamide and Benzthiazide in the Sydney 2000 Olympic Games; 3. H. TRABELSI, I. TRABELSI, F. RAOUAFI, K. BOUZOUITA: Simultaneous Determination of Ephedrines in Urine by RP-HPLC; 4. F. BOTRÈ, M. MAZZARINO, E. PODESTÀ, F. ROSSI, F. MAZZEI: Is there a Place for Electroanalysis in the Antidoping Laboratory? 5. A.T. CAWLEY, G.J. TROUT, R. KAZLAUSKAS: Quantitation of Urinary Caffeine by GC/MS using 13C Caffeine as Internal Standard; 6. G. VAJIALA, M. LAMOR, B. CHITIMIA: Benzbromarone, a Possible Masking Agent of Anabolic Androgenic Steroids (2); 7. C. MANZONI, D. DE BOER, M. CALÇADA, I. PÓVOA, C. MARTINS, L.J.A.L.DOS REYS: Some Analytical Data Relevant for the Detection of 1-Benzylpiperazine, a Pharmacological Alternative for Amphetamine; 8. H.BAÉZ, C. CAMARGO, H. OSORIO: Simultaneous Determination and Quantitation of Cocaine Metabolites in Urine by GC/MS. Could Possibly Some of Them Be Used as New Reliable Markers of Cocaine Ingestion in Addition to Benzoylecgonine ? 9. L.M.P. DAMASCENO, R.M.A. BENTO, L.N.L.F. GOMES, R. DE LA TORRE, F.R. AQUINO NETO: Mesocarb Analysis Revisited; 10. G. SIGMUND, , G. OPFERMANN, I. SEINSCH, W. SCHÄNZER: Detection of Bupropion and Metabolites; 11. F. BOTRÈ, L. AMENDOLA, M. MAZZARINO, F. MOLAIONI, B. NERI, F. ROSSI, G. DE FEO: One Year of Nandrolone at the Antidoping Laboratory of Rome; 12. M. MAZZARINO, F. BOTRÈ, F. ROSSI, E.PAONE, J. PECORI-GIRALDI: Lack of Increased Diuresis after Topical Administration of the Carbonic Anhydrase Inhibitor Dorzolamide; 13. S. WESTWOOD, D. HANCOCK, B. KING, H. WANG, J. MAKRYNIKOLAS, S. STARLING: Stability Trials of Anabolic Steroid Reference Materials; 14. Y. XU, Y. QIN, S. PENG: Observation of Degradation of Some Doping Agents in Plasma; 15. E. SETIAWATI, F.D. SUYATNA, M.S. WIRIA, D. ULAMSARI: Profile of Urinary Excretion in Indonesian Volunteers after DHEA Administration; 16. R.M.A. BENTO, L.M.P. DAMASCENO, H.M.G. PEREIRA, L.N.L.F. GOMES, J.N. CARDOSO, F.R. DE AQUINO NETO: Evaluation of Some Energetic and Nutritional Supplements in Brazil: Can They Originate a Positive Case for Stimulants in Doping Control? 17. M.S. HIFNAWY, S.M. AZZAM, S.N. SOLIMAN, I.B. SHAHEED, S.M. ABDEL LATIF: Egyptian Desert Truffles, Androgenic Natural Product, Possibility of Abusing in Sport; 18. C.P. D´ANGELO, G.M. CABALLERO, O. TEME CENTURIÓN, C. DI NARDO, G.G. CASES, C.F. OCHOA, L. CHINCHILLA, E. CECCARELLI, M. E. ZADORECKI, G. ZÁCCARO, M. SOL FRAGUÍO: Steroidprofile and Peptides Hormones in Urine of Argentine Athletes; 19. B. BIALAS, D. SCHWENKE, W. SCHÄNZER, R.K. MÜLLER: Diurnal Variation of Indirect Parameters for the Detection of Recombinant Human Erythropoietin Abuse in Athletes; 20. M. WU, X. LIU, S. WANG, L. SHEN: Detection of LH (luteinizing hormone) in Sport - One Year Statistics; 21. C. FOURACRE, R. KAZLAUSKAS: Diuretics Screening and Confirmation Using LC/MS/MS