TY  - JOUR
AU  - Baj, Z.
A2  - Baj, Z.
A2  - Kantorski, J.
A2  - Majewska, E.
A2  - Zeman, K.
A2  - Pokoca, L.
A2  - Fornalczyk, E.
A2  - Tchorzewski, H.
A2  - Sulowska, Z.
A2  - Lewicki, R.
DB  - BISp
DP  - BISp
KW  - Ausdauersport
KW  - Granulozyt, neutrophiler
KW  - Immunologie
KW  - Immunsystem
KW  - Leistungssportler
KW  - Leukozytenzahl
KW  - Lymphozyt
KW  - Radsport
KW  - Sportmedizin
KW  - Trainingsperiode
KW  - Trainingswirkung
LA  - eng
TI  - Immunological status of competitive cyclists before and after the training season
TT  - Immunstatus von Radrennsportlern vor und nach einer Trainingssaison
PY  - 1994
N2  - The total number of leucocytes, T lymphocyte subsets, mitogen induced proliferation of lymphocytes, IL-2 generation, adherence capacity and chemiluminescence of granulocytes were measured and a leukergy test performed in fifteen young cyclists. The investigations were carried out at rest at the beginning of a training season and after six months of intensive training and a racing season, cycling approximately 500 km a week. Baseline values of the tested immune parameters were within the range observed in 16 non-trained healthy controls except significantly increased non stimulated neutrophil chemiluminescence. The second cyclo-ergometer test in August showed a marked improvement in the performance capacity of the cyclists. Significant decrease in absolute numbers of CD3+ and CD4+ cells, diminished IL-2 generation and fMLP and PMA stimulated chemiluminescence of neutrophils were noted. Surprisingly, a marked increase in lymphocyte proliferation induced by PHA and anti-CD3 MoAb and normalisation in non stimulated neutrophil chemiluminescence were also abserved at rest after the training season. We conclude that long-lasting intensive training may result in significant alterations in lymphocyte number and composition and in neutrophil oxidative burst capacity, but their actual significance for immunity is seen controversially.                           Verf.-Referat
L2  - https://dx.doi.org/10.1055/s-2007-1021067
DO  - 10.1055/s-2007-1021067
SP  - S. 319-324
SN  - 0172-4622
JO  - International journal of sports medicine
IS  - 6
VL  - 15
M3  - Gedruckte Ressource
M3  - Elektronische Ressource (online)
ID  - PU199511103519
ER  -