Nachweis des Collagenabbaus anhand der Crosslinks - ein Marker fuer die Knochenresorption auch bei Ausdauersportlern
| Englischer übersetzter Titel: | Verification of collagen-degradation with crosslinks - an indicator of bone resorption in endurance athletes? |
|---|---|
| Autor: | Riedel, H.; Kull, S.; Zapf, J. |
| Herausgeber: | Liesen, Heinz; Weiß, Michael; Baum, Matthias |
| Erschienen in: | Regulations- und Repairmechanismen : 33. Deutscher Sportärztekongress Paderborn 1993 |
| Veröffentlicht: | Köln: Dt. Ärzte-Verl. (Verlag), 1994, 1994. S. 654-656, Abb., Lit., Lit. |
| Format: | Literatur (SPOLIT) |
| Publikationstyp: | Sammelwerksbeitrag |
| Medienart: | Gedruckte Ressource |
| Sprache: | Deutsch |
| ISBN: | 3769103084 |
| Schlagworte: | |
| Online Zugang: | |
| Erfassungsnummer: | PU199503075849 |
| Quelle: | BISp |
Abstract des Autors
Type I collagen as the main constituent of organic bone matrix is composed of a triple helix with three peptide chains in which they are linked to and stabilized by each other by the so-called crosslinks (pyridinoline (PYD), deoxy-pyridinoline (D-PYD)). For this reason and due to the recently available essays on the classification of crosslinks as ELISA (Fa. Metra, Biosystems Inc.) we studied the elimination of PYD and creatinine in a total of 72 female endurance athletes and 27 patients with and without osteoporosis (average age 40.4 +/- 11.0 years) from 2-h-morning urine with a quotient of PYD/mmol creatinin mean of 56.09 +/- 16.1 for all the persons examined (min. 8.1, max 91.4). No correlative connections between the elimination of PYD and bone mineral density have been found. Verf.-Referat