Morphologische Regulationsmechanismen des Knochenumbaus und ihre Bedeutung fuer die Osteoporose
| Englischer übersetzter Titel: | Morphological mechanisms of bone remodeling and their role in osteoporosis |
|---|---|
| Autor: | Amling, M.; Vogel, M.; Ritzel, H.; Grote, H.J.; Hahn, M.; Delling, G. |
| Herausgeber: | Liesen, Heinz; Weiß, Michael; Baum, Matthias |
| Erschienen in: | Regulations- und Repairmechanismen : 33. Deutscher Sportärztekongress Paderborn 1993 |
| Veröffentlicht: | Köln: Dt. Ärzte-Verl. (Verlag), 1994, 1994. S. 647-650, Abb., Lit., Lit. |
| Format: | Literatur (SPOLIT) |
| Publikationstyp: | Sammelwerksbeitrag |
| Medienart: | Gedruckte Ressource |
| Sprache: | Deutsch |
| ISBN: | 3769103084 |
| Schlagworte: | |
| Online Zugang: | |
| Erfassungsnummer: | PU199503075847 |
| Quelle: | BISp |
Abstract des Autors
Analysis of the complete spine and iliac crest bone biopsy of 26 skelettally intact autopsy cases and 11 female patients with clinically proven osteoporosis showed that the diminution of bone mass is not due to a significant thinning of trabeculae - the mean trabecular thickness is 120 micro/m - but to a loss of trabecular plates which are transformed to trabecular rods and to the loss of whole trabeculae. Three-dimensional analyses of trabecular bone structure in osteoporosis reveal that perforations of individual trabeculae are common. They result in a reduction of the stability of trabecular network by inducing mechanically incompetent trabeculae. Reparative mechanisms, like microcallus formations, may also lead to errors when measuring trabecular bone density. Verf.-Referat