Plasma elastase-alpha1-antitrypsin, neopterin, tumor necrosis factor, and soluble interleukin-2 receptor after prolonged exercise
Deutscher übersetzter Titel: | Elastase-alpha1-Antitrypsin, Neopterin, Tumor-Nekrose-Faktor und loeslicher Interleukin-2-Rezeptor im Plasma nach Ausdauerbelastung |
---|---|
Autor: | Dufaux, Bertin; Order, U. |
Erschienen in: | International journal of sports medicine |
Veröffentlicht: | 10 (1989), 6, S. 434-438, Lit. |
Format: | Literatur (SPOLIT) |
Publikationstyp: | Zeitschriftenartikel |
Medienart: | Gedruckte Ressource Elektronische Ressource (online) |
Sprache: | Englisch |
ISSN: | 0172-4622, 1439-3964 |
DOI: | 10.1055/s-2007-1024939 |
Schlagworte: | |
Online Zugang: | |
Erfassungsnummer: | PU199005043441 |
Quelle: | BISp |
Abstract
The effects of a 2.5-h running test on the plasma concentrations of elastase-alpha1-antitrypsin, neopterin, tumor necrosis factor, and soluble interleukin-2 receptor were evaluated in eight healthy young male subjects. Neopterin was measured by radioimmunoassay, elastase-alpha1-antitrypsin, tumor necrosis factor, and soluble interleukin-2 receptor by enzyme immunoassay. The post-exercise values were corrected for plasma volume changes which were calculated from hematokrit and hemoglobin values. Compared with the concentrations before exercise, elastase-alpha1-antitrypsin values were significantlyy increased during the run (1 h after the start) as well as during the first few hours after the end of the running test. A significant increase of tumor necrosis factor and neopterin was observed 1 h after the end and 1,3 and 24 h after the end of the running test, respectively, and soluble interleukin-2 receptor concentrations were significantly elevated 1 and 2 days after exercise. The increase of elastase-alpha1-antitrypsin, neopterin, tumor necrosis factor, and soluble interleukin-2 receptor supports the concept of a functional involvement of polymorphonuclear neutrophils and an activation of macrophages and T-lymphocytes after prolonged exercise. Verf.-Referat