Plasma elastase-alpha1-antitrypsin, neopterin, tumor necrosis factor, and soluble interleukin-2 receptor after prolonged exercise

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Bibliographic Details
Title translated into German:Elastase-alpha1-Antitrypsin, Neopterin, Tumor-Nekrose-Faktor und loeslicher Interleukin-2-Rezeptor im Plasma nach Ausdauerbelastung
Author:Dufaux, B.; Order, U.
Published in:International journal of sports medicine
Published:10 (1989), 6 , S. 434-438, Lit.
Format: Publications (Database SPOLIT)
Publication Type: Journal article
Media type: Print resource
Language:English
ISSN:0172-4622, 1439-3964
Keywords:
Online Access:
Identification number:PU199005043441
Source:BISp

Abstract

The effects of a 2.5-h running test on the plasma concentrations of elastase-alpha1-antitrypsin, neopterin, tumor necrosis factor, and soluble interleukin-2 receptor were evaluated in eight healthy young male subjects. Neopterin was measured by radioimmunoassay, elastase-alpha1-antitrypsin, tumor necrosis factor, and soluble interleukin-2 receptor by enzyme immunoassay. The post-exercise values were corrected for plasma volume changes which were calculated from hematokrit and hemoglobin values. Compared with the concentrations before exercise, elastase-alpha1-antitrypsin values were significantlyy increased during the run (1 h after the start) as well as during the first few hours after the end of the running test. A significant increase of tumor necrosis factor and neopterin was observed 1 h after the end and 1,3 and 24 h after the end of the running test, respectively, and soluble interleukin-2 receptor concentrations were significantly elevated 1 and 2 days after exercise. The increase of elastase-alpha1-antitrypsin, neopterin, tumor necrosis factor, and soluble interleukin-2 receptor supports the concept of a functional involvement of polymorphonuclear neutrophils and an activation of macrophages and T-lymphocytes after prolonged exercise. Verf.-Referat