Impaired cardiovascular responses to graded exercise in diabetic autonomic neuropathy

Gespeichert in:
Bibliographische Detailangaben
Deutscher übersetzter Titel:Verminderte Herz-Kreislauf-Reaktionen auf abgestufte koerperliche Belastung bei autonomer diabetischer Neuropathie
Autor:Hilsted, Jannik; Galbo, Henrik; Christensen, Niels Juel
Erschienen in:Diabetes
Veröffentlicht:28 (1979), 4, S. 313-319, Lit.
Format: Literatur (SPOLIT)
Publikationstyp: Zeitschriftenartikel
Medienart: Gedruckte Ressource
Sprache:Englisch
ISSN:0012-1797, 1939-327X
Schlagworte:
Online Zugang:
Erfassungsnummer:PU198003010923
Quelle:BISp
TY  - JOUR
AU  - Hilsted, Jannik
A2  - Hilsted, Jannik
A2  - Galbo, Henrik
A2  - Christensen, Niels Juel
DB  - BISp
DP  - BISp
KW  - Belastung, körperliche
KW  - Betarezeptorenblockade
KW  - Blutdruck, systolischer
KW  - Diabetes, juveniler
KW  - Diabetes mellitus
KW  - Fahrradergometerbelastung
KW  - Herz-Kreislauf-System
KW  - Herzfrequenz
KW  - Nervensystem, sympathisches
KW  - Neuropathie
KW  - Sauerstoffaufnahme, maximale
KW  - Sportmedizin
LA  - eng
TI  - Impaired cardiovascular responses to graded exercise in diabetic autonomic neuropathy
TT  - Verminderte Herz-Kreislauf-Reaktionen auf abgestufte koerperliche Belastung bei autonomer diabetischer Neuropathie
PY  - 1979
N2  - Six juvenile diabetics (age, 31 +/- 2 yr (mean and SEM); duration of diabetes,15+/-4 yr) with signs of autonomic neuropathy (decreased beat-to-beat variation in heart rate during deep breathing) and seven control patients of similar age (27 +/- 1yr) and duration of diabetes (14 +/- 2 yr) performed graded exercise on an ergometer cycle. Resting heart rate was higher and the increase in heart rate at the lowest work load (50 W) was diminished in patients with autonomic neuropathy compared with control patients, indicating a vagal defect. The relationships in autonomic neuropathy between heart rate and systolic blood pressure, respectively, and relative work load (expressed as oxygen uptake - in percent - of individual maximal oxygen uptake) were identical with previous findings in normal subjects during betaadrenergic receptor blockade, indicating impaired sympathetic activity. Maximal heart rate was 157 +/- 9. min in automatic neuropathy and 181 +/- 4 in controls, maximal systolic blood pressure was 179 +/- 11 mmHg and 197 +/- 5, respectively. The greatest tolerable work load was significantly less in patients with autonomic neuropathy (125 +/- 13 vs. 161 +/- 9 w). Similarly, maximal oxygen uptake was reduced (1.68 +/- 0.21 vs. 278 +/- 0.18 l/min, 25 +/- 3 vs. 38 +/- 2ml/min/kg). Verf.-Referat (gekuerzt)
SP  - S. 313-319
SN  - 0012-1797
JO  - Diabetes
IS  - 4
VL  - 28
M3  - Gedruckte Ressource
ID  - PU198003010923
ER  -