Abstract des Autors

One of the crucial issues related to antidoping is the possibility of sample manipulation that can results as biochemical alteration of the sample or its substitution with a sample from another person. An athlete, as a consequence of a detected positivity, can make raise doubts about the attribution of the urine sample to his person. So, it could be necessary to introduce methods which make it possible to attribute a sample to a particular individual. In this study, two systems of identification of urine samples were compared, one that considers the study of steroid profile and the other that it is based on forensic DNA typing. The specific problems associated with the stability of urine samples that are subjected to doping control routine were considered to highlight any efficacy limitation and difference. It was demonstrated the utility of the DNA typing when the degradation of the urinary sample, subjected to preservation, does not allow the sample-individual linkage by steroidal profile.