Expression of extracellular matrix components and related growth factors in human tendon and muscle after acute exercise
Gespeichert in:
| Deutscher übersetzter Titel: | Die Expression von extrazellulären Matrixkomponenten und der damit verbundenen Wachstumsfaktoren in menschlichen Sehnen und Muskulatur nach akutem Training |
|---|---|
| Autor: | Heinemeier, Katja M.; Bjerrum, S.S.; Schjerling, P.; Kjær, Michael |
| Erschienen in: | Scandinavian journal of medicine & science in sports |
| Veröffentlicht: | 23 (2013), 3, S. e150-e161, Lit. |
| Format: | Literatur (SPOLIT) |
| Publikationstyp: | Zeitschriftenartikel |
| Medienart: | Elektronische Ressource (online) Gedruckte Ressource |
| Sprache: | Englisch |
| ISSN: | 0905-7188, 1600-0838 |
| DOI: | 10.1111/j.1600-0838.2011.01414.x |
| Schlagworte: | |
| Online Zugang: | |
| Erfassungsnummer: | PU201512009185 |
| Quelle: | BISp |
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Scandinavian journal of medicine & science in sports |
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Scandinavian journal of medicine & science in sports, 2013, 3 |
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PU201512009185 |
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Expression of extracellular matrix components and related growth factors in human tendon and muscle after acute exercise |
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bisparticle |
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2013 |
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2013 |
| language |
eng |
| title |
Expression of extracellular matrix components and related growth factors in human tendon and muscle after acute exercise |
| spellingShingle |
Expression of extracellular matrix components and related growth factors in human tendon and muscle after acute exercise Belastung, mechanische Biochemie Extremität, untere Genexpression Kollagen M. vastus lateralis Markersubstanz Muskelbiopsie Protein Proteoglykane Sehne Sehnenfaser Skelettmuskulatur Sportmedizin Sportwissenschaft Varianzanalyse Wachstumsfaktor Zellstoffwechsel Zellwachstum |
| title_sort |
expression of extracellular matrix components and related growth factors in human tendon and muscle after acute exercise |
| title_short |
Expression of extracellular matrix components and related growth factors in human tendon and muscle after acute exercise |
| title_alt |
Die Expression von extrazellulären Matrixkomponenten und der damit verbundenen Wachstumsfaktoren in menschlichen Sehnen und Muskulatur nach akutem Training |
| title_alt_lang |
deu |
| media_type |
Elektronische Ressource (online) Gedruckte Ressource |
| city |
Oxford |
| abstract |
Acute kicking exercise induces collagen synthesis in both tendon and muscle in humans, but it is not known if this relates to increased collagen transcription and if other matrix genes are regulated. Young men performed 1 h of one-leg kicking at 67% of max workload. Biopsies were taken from the patellar tendon and vastus lateralis muscle of each leg at 2 (n = 10), 6 (n = 11), or 26 h (n = 10) after exercise. Levels of messenger ribonucleic acid mRNA for collagens, noncollagenous matrix proteins, and growth factors were measured with real-time reverse transcription polymerase chain reaction. In tendon, gene expression was unchanged except for a decrease in insulin-like growth factor-IEa (IGF-IEa; P < 0.05). In muscle, collagen expression was not significantly altered, while levels of connective tissue growth factor (CTGF), IGF-IEa, transforming growth factor-β1, -2 (TGF-β), and the TGF-β receptor II mRNA were increased (P < 0.05). Matrix components tenascin-C, fibronectin, and decorin were also induced in loaded muscle (P < 0.05), while fibromodulin was unaffected. In conclusion, the relatively robust changes in matrix components and related growth factors in muscle indicate a stimulation of extracellular matrix even with moderate exercise. However, in tendon tissue, this exercise model does not appear to induce any anabolic response on the transcriptional level. Verf.-Referat |
| abstract_lang |
eng |
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abstract |
| author2 |
Heinemeier, Katja M. Bjerrum, S.S. Schjerling, P. Kjær, Michael |
| author_facet |
Heinemeier, Katja M. Bjerrum, S.S. Schjerling, P. Kjær, Michael |
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Autor Autor Autor Autor |
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P178118 |
| author_author_facet |
Heinemeier, Katja M. Bjerrum, S.S. Schjerling, P. Kjær, Michael |
| author2-synonym |
Kjaer, Michael ,Kjaer, M. ,Kjær, M. |
| author2_hierarchy_facet |
0/Autor/ 1/Autor/Heinemeier, Katja M./ 0/Autor/ 1/Autor/Bjerrum, S.S./ 0/Autor/ 1/Autor/Schjerling, P./ 0/Autor/ 1/Autor/Kjær, Michael/ |
| doi |
10.1111/j.1600-0838.2011.01414.x |
| spelling |
10.1111/j.1600-0838.2011.01414.x 0905-7188 1600-0838 SMSSEO 1077418-x Belastung, mechanische Biochemie Extremität, untere Genexpression Kollagen M. vastus lateralis Markersubstanz Muskelbiopsie Protein Proteoglykane Sehne Sehnenfaser Skelettmuskulatur Sportmedizin Sportwissenschaft Varianzanalyse Wachstumsfaktor Zellstoffwechsel Zellwachstum biochemistry cell growth cell metabolism collagen gene expression growth factor lower extremity m. vastus lateralis marker substance mechanic load muscle biopsy protein proteoglycans skeletal muscles sport science sports medicine tendinous fibre tendon variance analysis Medizin Geschichte der Medizin Untersuchung, sportmedizinische Wasserdampf Theorie der Körpererziehung Theorie der Leibesübungen Theorie der Leibeserziehung Eiweiss Plasmaprotein Belastung Muskulatur Skelettmuskel Muskel Biopsie Bein Beinversehrter Beinigkeit Beinamputierter Varianz exercise science sport and exercise science cell proliferation lower limb vastus lateralis muscle Expression of extracellular matrix components and related growth factors in human tendon and muscle after acute exercise PU201512009185 201512009185 |
| url |
http://dx.doi.org/10.1111/j.1600-0838.2011.01414.x https://dx.doi.org/10.1111/j.1600-0838.2011.01414.x |
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misc fulltext |
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0905-7188 1600-0838 |
| coden |
SMSSEO |
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1077418-x |
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0/Großbritannien/ 1/Großbritannien/England/ |
| topic |
Belastung, mechanische Biochemie Extremität, untere Genexpression Kollagen M. vastus lateralis Markersubstanz Muskelbiopsie Protein Proteoglykane Sehne Sehnenfaser Skelettmuskulatur Sportmedizin Sportwissenschaft Varianzanalyse Wachstumsfaktor Zellstoffwechsel Zellwachstum |
| topic_facet |
Belastung, mechanische Biochemie Extremität, untere Genexpression Kollagen M. vastus lateralis Markersubstanz Muskelbiopsie Protein Proteoglykane Sehne Sehnenfaser Skelettmuskulatur Sportmedizin Sportwissenschaft Varianzanalyse Wachstumsfaktor Zellstoffwechsel Zellwachstum |
| topic_en |
biochemistry cell growth cell metabolism collagen gene expression growth factor lower extremity m. vastus lateralis marker substance mechanic load muscle biopsy protein proteoglycans skeletal muscles sport science sports medicine tendinous fibre tendon variance analysis |
| topic_en_facet |
biochemistry cell growth cell metabolism collagen gene expression growth factor lower extremity m. vastus lateralis marker substance mechanic load muscle biopsy protein proteoglycans skeletal muscles sport science sports medicine tendinous fibre tendon variance analysis |
| synonym |
Medizin Geschichte der Medizin Untersuchung, sportmedizinische Wasserdampf Theorie der Körpererziehung Theorie der Leibesübungen Theorie der Leibeserziehung Eiweiss Plasmaprotein Belastung Muskulatur Skelettmuskel Muskel Biopsie Bein Beinversehrter Beinigkeit Beinamputierter Varianz |
| synonym_en |
exercise science sport and exercise science cell proliferation lower limb vastus lateralis muscle |
| journal_facet |
Scandinavian journal of medicine & science in sports |
| container_title |
Scandinavian journal of medicine & science in sports |
| container_volume |
23 |
| container_issue |
3 |
| container_start_page |
S. e150-e161 |
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1 |
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BISp |
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JO00000001282 |
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2013 |
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3 |
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13,266428 |