Endothelial (dys)function : the target of physical exercise for prevention and treatment of cardiovascular disease
Gespeichert in:
Deutscher übersetzter Titel: | Endothelial (Dys) Funktion : das Trainingsziel für Prävention und Behandlung von Herz-Kreislauferkrankungen |
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Autor: | Pigozzi, F.; Rizzo, M.; Fagnani, F.; Parisi, A.; Spataro, A.; Casasco, M.; Borrione, P. |
Erschienen in: | The Journal of sports medicine and physical fitness |
Veröffentlicht: | 51 (2011), 2, S. 260-267, Lit. |
Format: | Literatur (SPOLIT) |
Publikationstyp: | Zeitschriftenartikel |
Medienart: | Gedruckte Ressource Elektronische Ressource (online) |
Sprache: | Englisch |
ISSN: | 0022-4707, 1827-1928 |
Schlagworte: | |
Online Zugang: | |
Erfassungsnummer: | PU201303001521 |
Quelle: | BISp |
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PU201303001521 |
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format |
Literatur |
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2024-03-28T15:03:43Z |
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2013-03-04T12:09:02Z |
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BISp |
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Zeitschriftenartikel |
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JO00000000824 |
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JOI201100020000824 |
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The Journal of sports medicine and physical fitness |
hierarchy_parent_title |
The Journal of sports medicine and physical fitness, 2011, 2 |
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PU201303001521 |
is_hierarchy_title |
Endothelial (dys)function : the target of physical exercise for prevention and treatment of cardiovascular disease |
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0260 |
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bisparticle |
publishDate |
2011 |
publishDate_facet |
2011 |
language |
eng |
title |
Endothelial (dys)function : the target of physical exercise for prevention and treatment of cardiovascular disease |
spellingShingle |
Endothelial (dys)function : the target of physical exercise for prevention and treatment of cardiovascular disease Aktivität, körperliche Endothelin Herz-Kreislauf-System Krankheit, chronische Kreislauferkrankung Prävention Sportmedizin Training, sportliches Trainingseffektivität Untersuchung, empirische |
title_sort |
endothelial dysfunction the target of physical exercise for prevention and treatment of cardiovascular disease |
title_short |
Endothelial (dys)function : the target of physical exercise for prevention and treatment of cardiovascular disease |
title_alt |
Endothelial (Dys) Funktion : das Trainingsziel für Prävention und Behandlung von Herz-Kreislauferkrankungen |
title_alt_lang |
deu |
media_type |
Gedruckte Ressource Elektronische Ressource (online) |
city |
Turin |
spelling |
Torino 0022-4707 1827-1928 JMPFA 410823-1 Aktivität, körperliche Endothelin Herz-Kreislauf-System Krankheit, chronische Kreislauferkrankung Prävention Sportmedizin Training, sportliches Trainingseffektivität Untersuchung, empirische cardiovascular disease cardiovascular system chronic disease empirical investigation endothelin physical activity prevention sports medicine sport training training effectiveness Medizin Geschichte der Medizin Untersuchung, sportmedizinische Wasserdampf Ausbildung, sportliche Bewegungstraining Schulung Sportarttraining Training Training, motorisches Training, sportartspezifisches Trainingsbetrieb Trainingspraxis Trainingsprozess Trainingssystem Trainingstechnologie Trainingszeit Trainingsziel Gesundheitsvorsorge Maßnahme, präventive Präventivmedizin Prophylaxe Vorbeugung Gesundheitsförderung Kreislauf-System Herz-Kreislauf-Erkrankung Trainingserfolg Aktivität, motorische Bewegungsaktivität Aktivität Empirie Empirismus Untersuchung, experimentelle Untersuchung training for sport effectiveness of training empirical study Endothelial (dys)function : the target of physical exercise for prevention and treatment of cardiovascular disease PU201303001521 201303001521 |
abstract |
AIM: Endothelial dysfunction has been recognized as the early event and the common feature of chronic disorders associated with increased risk for atherosclerotic heart diseases. While the beneficial effects of aerobic, moderate-intensity exercise on endothelial function are very well assessed, an intriguing doubt exists about the effects of long-term high-intensity physical activity. The aim of the present study was to compare recent findings of our group concerning homocysteine levels in athletes to available data in literature in order to clarify the meaning of such apparent metabolic paradox.
METHODS: The studied population included 185 athletes: 180 healthy age and sex matched subjects served as control group. The assessed variables included homocysteine, folate, vitamin B12, total and HDL cholesterol, LDH, CPK and IL-6. Results were compared to available data in literature.
RESULTS: The prevalence of hyperhomocysteinemia (>15 µmol/L) in athletes and controls was 55% and 15%, respectively. In the studied population, no correlation was found between homocysteine and all the other investigated variables.
CONCLUSION: The present results suggest that intensive physical training could induce a pathological increase of homocysteine levels. With this regard, it has been suggested that the observed increases of cardio-vascular risk factors in athletes could represent an adaptative feature marker of muscle demand but would not actually lead to endothelial damage. This remains, however, a speculative hypothesis and further analysis are needed in order to clarify the clinical significance of those observations in order to better preserve the athletes immediate and future health. Verf.-Referat |
abstract_lang |
eng |
abstract_type |
author |
author2 |
Pigozzi, F. Rizzo, M. Fagnani, F. Parisi, A. Spataro, A. Casasco, M. Borrione, P. |
author_facet |
Pigozzi, F. Rizzo, M. Fagnani, F. Parisi, A. Spataro, A. Casasco, M. Borrione, P. |
author2-role |
Autor Autor Autor Autor Autor Autor Autor |
author2-authorityid |
|
author_author_facet |
Pigozzi, F. Rizzo, M. Fagnani, F. Parisi, A. Spataro, A. Casasco, M. Borrione, P. |
author2-synonym |
|
author2_hierarchy_facet |
0/Autor/ 1/Autor/Pigozzi, F./ 0/Autor/ 1/Autor/Rizzo, M./ 0/Autor/ 1/Autor/Fagnani, F./ 0/Autor/ 1/Autor/Parisi, A./ 0/Autor/ 1/Autor/Spataro, A./ 0/Autor/ 1/Autor/Casasco, M./ 0/Autor/ 1/Autor/Borrione, P./ |
url |
https://pubmed.ncbi.nlm.nih.gov/21681161/ |
url-type |
fulltext |
url-free |
0 |
issn |
0022-4707 1827-1928 |
coden |
JMPFA |
zdb |
410823-1 |
location_hierarchy_facet |
0/Italien/ |
topic |
Aktivität, körperliche Endothelin Herz-Kreislauf-System Krankheit, chronische Kreislauferkrankung Prävention Sportmedizin Training, sportliches Trainingseffektivität Untersuchung, empirische |
topic_facet |
Aktivität, körperliche Endothelin Herz-Kreislauf-System Krankheit, chronische Kreislauferkrankung Prävention Sportmedizin Training, sportliches Trainingseffektivität Untersuchung, empirische |
topic_en |
cardiovascular disease cardiovascular system chronic disease empirical investigation endothelin physical activity prevention sports medicine sport training training effectiveness |
topic_en_facet |
cardiovascular disease cardiovascular system chronic disease empirical investigation endothelin physical activity prevention sports medicine sport training training effectiveness |
synonym |
Medizin Geschichte der Medizin Untersuchung, sportmedizinische Wasserdampf Ausbildung, sportliche Bewegungstraining Schulung Sportarttraining Training Training, motorisches Training, sportartspezifisches Trainingsbetrieb Trainingspraxis Trainingsprozess Trainingssystem Trainingstechnologie Trainingszeit Trainingsziel Gesundheitsvorsorge Maßnahme, präventive Präventivmedizin Prophylaxe Vorbeugung Gesundheitsförderung Kreislauf-System Herz-Kreislauf-Erkrankung Trainingserfolg Aktivität, motorische Bewegungsaktivität Aktivität Empirie Empirismus Untersuchung, experimentelle Untersuchung |
synonym_en |
training for sport effectiveness of training empirical study |
journal_facet |
The Journal of sports medicine and physical fitness |
container_title |
The Journal of sports medicine and physical fitness |
container_volume |
51 |
container_issue |
2 |
container_start_page |
S. 260-267 |
has_references |
1 |
institution |
BISp |
journal_fac |
JO00000000824 |
journal_year |
2011 |
journal_issue |
2 |
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1810937313213022208 |
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13,263606 |