Abstract

Der 28. Manfred Donike Workshop für Dopinganalyse fand vom 07. bis 12. März 2010 in Köln statt. Der im selben Jahr veröffentlichte Kongressband enthält die folgenden Beiträge: 1. M. Kolmonen, A. Leinonen, T. Kuuranne, A. Pelander, I. Ojanperä: Quantitation of morphine and its glucuronides in human urine by HILIC-TOFMS; 2. I. Möller, A. Thomas, S. Beuck, G. Rodchenkov, W. Bornatsch, H. Geyer, W. Schänzer, M. Thevis: In-vitro metabolism of GW1516 and implementation of its major metabolites in routine doping controls; 3. R. Kazlauskas and V. Agon: ASDTL Supplements Project 2009; 4. M.K. Parr, P. Diel, O. Zierau, W. Schänzer: Investigations regarding the WADA classification of the supplement ingredient androsta-1,4,6-triene-3,17-dione; 5. D.B. Paulsen, D.E. Rollins, R. Fowles, J.D. Valiante, J.P. Danaceau: Steroid profiling among National Football League players; 6. L. Lootens, P. Van Eenoo, O.J. Pozo, P. Meuleman, G. Leroux-Roels, F.T. Delbeke: Applications of in vivo urinary steroid detection in uPA+/+-SCID chimeric mice; 7. T. Sten, M. Kurkela, T. Kuuranne, A. Leinonen, M. Finel: UDP-Glucuronosyltransferases in conjugation of 5α- and 5β-androstane steroids; 8. M.K. Parr, G. Fußhöller, M. Gütschow, C. Hess, W. Schänzer: GC-MS(/MS) investigations on long-term metabolites of 17-methyl steroids; 9. I. Gavrilović, R.J. Ansell, A.D. Brailsford, D.A.Cowan. A.T. Kicman: Molecularly imprinted polymers selective for testosterone; potential application for GC/C/IRMS sample clean-up; 10. C. Reichel: The overlooked difference: Structural basis for a mass spectrometry-based dopingtest for recombinant erythropoietins; 11. C. Reichel, E. Benetka, T. Geisendorfer, V. Scheiblhofer, F. Abzieher: Heparin: more than an anticoagulant - interference of heparin on IEF-PAGE of erythropoietins; 12. R.I.G. Holt, I. Erotokritou-Mulligan, C.M. McHugh, E.E. Bassett, C. Bartlett, A. Fityan, J.L. Bacon, D.A. Cowan, P.H. Sönksen: The GH-2004 project: ethnicity does not affect the response of IGF—I and procollagen III N-terminal propeptide to the administration of exogenous growth hormone (GH) in amateur athletes; 13. M. Okano, Y. Nishitani, M. Sato, A. Ikekita, S. Kageyama: bGH isoform profiles in Japanese male subject — Reference population, rhGH administration and influence of GH secretagogue -; 14. A. Thomas, M. Kohler, P. Delahaut, W. Schänzer, M. Thevis: Preliminary results for the development of a peptide screening method by means of LC-MS/MS; 15. L. Harju, T. Kuuranne, A. Leinonen: Applicability of anthrone dyeing microtiter method for screening of hydroxyethyl starch and dextran — a deeper insight; 16. I.I. Sukhanova, M.A. Dikunets, G.M. Rodchenkov: Sample preparation of urine samples for liquid chromatography-tandem mass spectrometry using functionalized ferromagnetic beads; 17. T. Kaur, S. Dubey, M. Chakraborty, S. Jain, A. Beotra A, C.P. Shinde: Enantiomeric profiling of amphetamine and methamphetamine in sportspersons: a comparison of two chiral derivatization methods; 18. M. Sato, M. Okano, A. Ikekita, S. Kageyama: Quality control of the completeness of solid-phase extraction and hydrolysis using the deutrated internal standards — Screening procedure for stimulants, narcotics, diuretics, β-blockers and other dope agents in human urine by means of UPLC®/MS/MS; 19. A. Coetzee A, P.J. van der Merwe PJ: LC/MS/MS method for the detection of narcotic analgesics and non-steroidal anti-inflammatory drugs in human urine; 20. F. Donati, M. Mazzarino, X. de la Torre, F. Botrè: A fast pre-confirmation method for the detection of HBOCs by capillary electrophoresis and UV detection; 21. S. Strano Rossi, X. de la Torre, F. Molaioni, F. Botrè: Determination of sildenafil, vardenafil and tadalafil metabolites in human urine by GC/MS; 22. V.F. Sardela, P.D. de Oliveira, H.M.G. Pereira, F.R. Aquino Neto: Could a pseudoephedrine artifact lead to a misinterpretation? A pitfall in ephedrines analysis; 23. F. Marclay, M. Saugy: Determination of nicotine metabolites in urine by LC-MS/MS: trends of smoke and smokeless products exposure in ice hockey; 24. A.K. Orlovius, M.K. Parr. S. Guddat, M. Gütschow, M. Thevis, W. Schänzer: Detection of urinary phase-I and phase-II metabolites of ephedrine and oxilofrine by LC-MS/MS; 25. T. Sobolevsky, I. Prasolov, G. Rodchenkov: Detection of synthetic cannabinoid JWH-018 in urine; 26. I. Möller, A. Wintermeyer, A. Thomas, O. Krug, K. Bender, W. Schänzer, M. Thevis: In-vitro metabolism of the synthetic cannabinoid JWH-018 and implementation of its major metabolites in human doping controls; 27. G.A. Cavalcanti, F.D. Leal, M.C. Padilha, H.G.M. Pereira, X. de La Torre, F.R. Aquino Neto: Identification of urinary metabolites of exemestane oxidized in the exomethylene group by GC-MS; 28. A. Koch, G. Sigmund, S. Guddat, M. Thevis, W. Schänzer: Octopamine and biogenic amines; 29. S. Kaewklum, N. Suknet, K. Ditthayam, P. Wilairat, N. Chaikum: Determination of morphine in urine after the therapeutic administration of a common cough mixture, “Brown Mixture”, containing camphorated opium tincture; 30. M. Mazzarino, M.C. Braganò, X. de la Torre, F. Botrè: Effects of toremifene and tamoxifene on the urinary androgenic steroid profile in males and females; 31. T. Kaur, S. Jain, B. Bhula, R. Lal, A. Beotra, G.B.K.S. Prasad: Delta values of endogenous steroids in Indian population: establishing reference ranges; 32. U. Sjöberg, E. Palonek, M. Garle: Investigation of variation of deuterated testosterone and epitestosterone internal standards in screening; 33. V. Pop, I. Vâjială, M. Zorio, M. Lamor: Better recoveries in confirmation of stanozolol metabolites by LC/MS technique; 34. Walpurgis K., M. Kohler, A. Thomas, M. de Marees, J. Mester, W. Schänzer, M. Thevis: Effects of endurance exercise on the urinary proteome analyzed by 2D-PAGE and Orbitrap mass spectrometry; 35. Y. Dehnes, S. Lamon, M. Lönnberg: EPO immunoaffinity columns — a powerful tool for purifying erythropoietin and its recombinant analogues; 36. M. Okano, M. Sato, A. Ikekita, S. Kageyama: Determination of growth-hormone secretagogue pralmorelin (GHRP-2) and its metabolite in human urine by means of liquid chromatography/tandem mass spectronietry; 37. M. Kohler, A. Gotzmann, C. Görgens, U. Flenker, M. Thevis, W. Schänzer: Comparison of hGH serum concentrations of Caucasian and African top athletes: an ethnicity study; 38. L. Zhang, C. He, S. Yang, M. Vu, Y. Xu, J. Deng, Y. Cao, Y. Xing, Z. Yang: Preliminary excretion study of CERA in human urine and serums: which is the better matrix for detecting CERA abuse?; 39. M. Mazzarino, D. Jardines. S. Turi, X. de la Torre, F. Botrè: Effects of synthetic glucocorticoids administration on the urinary endogenous; 40. A. Beotra, Y.K. Gupta, S. Ahi, S. Dubey, A. Upadhyay, R. Priyadarshi, S. Jain: Preliminary studies on detection of corticosteroids in adulterated herbal drugs; 41. A. Beotra, S. Ahi, S. Dubey, A. Upadhyay, S. Jain G.B.K.S. Prasad: Determination of long term metabolites of methylprednisolone using liquid chromatography tandem mass spectrometry; 42. A. Beotra, S. Ahi, S. Dubey, A. Upadhyay, R. Priyadarshi, S. Jain: Metabolite identification and excretion profile of deflazacort on ultra performance liquid chromatography-tandem mass spectrometry; 43. F. Oueslati, S. Kraiem, A. Rezgui, M. Saidani, Z. Merhabane, M.H. Loueslati: Detection and excretion study of fluticasone propionate by liquid chromatography-mass spectrometry; 44. F. Oueslati, S. Kraiem, J. Jedidi, A.M. Ben Romdhane, H. Loueslati, N. Fenina: Study of methylprednisolone elimination profile in human urine using LC-ESI-MS/MS; 45. A.C.A. Silva, H.M.G. Pereira, F.R. Aquino Neto: Evidences of interindividual variability in phase II urinary excretion profiles of endogenous glucocorticosteroids; 46. B. Starcevic, A. Butch: Use of LC/MS3 on a new quadrupole linear trap mass spectrometer and high resolution chromatography to improve detection of anabolic steroids, glucocorticoids, anti-estrogenic agents, and β2-agonist and their metabolites; 47. S. Strano Rossi, X. de la Torre, F. Botrè: Speeding up the analytical times: fast GC analysis for stimulants, narcotics and drugs of abuse; 48. E. Virus, E. Semenistaya, T. Sobolevsky, G. Rodchenkov: Investigation of electrospray photoionization (ESPI) as new ‘universal’ ionization method for determination of doping agents by HPLC/Orbitrap mass spectrometry; 49. M.K. Parr, F. Westphal, Folker, F.D. Sönnichsen, H. Geyer, W. Schänzer: 1-DHEA identification in seized dietary supplement; 50. T. Sobolevsky, I. Prasolov, G. Rodchenkov: Designer stimulants recently identified on black market; 51. P. Cholbinski, W. Tszyrsznic, B. Wójcikowska-Wójcik, A. Pokrywka, D. Kwiatkowska: Validation of qualitative screening method for doping substances by using UPLC-QTOF system; 52. A. Jarek, D. Gorczyca, D. Kwiatkowska, A. Pokrywica: 100 years of anti-doping research. In memoriam of Alfons Bukowski; 53. E. Kochnova, I. Shevtsova, T. Sobolevsky, G. Rodchenkov: Software for analysis of urinary and blood parameters using Bayesian approach. AGa und Inhaltsverzeichnis