Single nucleotide polymorphisms in the myostatin (MSTN) and muscle creatine kinase (CKM) genes are not associated with elite endurance performance
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| Deutscher übersetzter Titel: | Einzelne Nukleotidpolymorphien in den Myostatin- (MSTN) und Muskelkreatinkinase- (CKM)Genen stehen nicht in Zusammenhang mit Spitzenausdauerleistung |
|---|---|
| Autor: | Doering, F.; Onur, S.; Kürbitz, C.; Boulay, M.R.; Perusse, L.; Rankinen, T.; Rauramaa, R.; Wolfarth, Bernd; Bouchard, C. |
| Erschienen in: | Scandinavian journal of medicine & science in sports |
| Veröffentlicht: | 21 (2011), 6, S. 841-845, Lit. |
| Format: | Literatur (SPOLIT) |
| Publikationstyp: | Zeitschriftenartikel |
| Medienart: | Gedruckte Ressource Elektronische Ressource (online) |
| Sprache: | Englisch |
| ISSN: | 0905-7188, 1600-0838 |
| DOI: | 10.1111/j.1600-0838.2010.01131.x |
| Schlagworte: | |
| Online Zugang: | |
| Erfassungsnummer: | PU201107005980 |
| Quelle: | BISp |
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PU201107005980 |
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Literatur |
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2023-11-24T08:44:54Z |
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JOI201100060001282 |
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Scandinavian journal of medicine & science in sports |
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Scandinavian journal of medicine & science in sports, 2011, 6 |
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PU201107005980 |
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Single nucleotide polymorphisms in the myostatin (MSTN) and muscle creatine kinase (CKM) genes are not associated with elite endurance performance |
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0841 |
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bisparticle |
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2011 |
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2011 |
| language |
eng |
| title |
Single nucleotide polymorphisms in the myostatin (MSTN) and muscle creatine kinase (CKM) genes are not associated with elite endurance performance |
| spellingShingle |
Single nucleotide polymorphisms in the myostatin (MSTN) and muscle creatine kinase (CKM) genes are not associated with elite endurance performance Ausdauerleistung Kreatin Myostatin Sauerstoffaufnahme Skelettmuskulatur Sportmedizin |
| title_sort |
single nucleotide polymorphisms in the myostatin mstn and muscle creatine kinase ckm genes are not associated with elite endurance performance |
| title_short |
Single nucleotide polymorphisms in the myostatin (MSTN) and muscle creatine kinase (CKM) genes are not associated with elite endurance performance |
| title_alt |
Einzelne Nukleotidpolymorphien in den Myostatin- (MSTN) und Muskelkreatinkinase- (CKM)Genen stehen nicht in Zusammenhang mit Spitzenausdauerleistung |
| title_alt_lang |
deu |
| media_type |
Gedruckte Ressource Elektronische Ressource (online) |
| city |
Oxford |
| abstract |
Maximal oxygen uptake (VO2max) is one of the most important determinants of elite endurance performance. VO2max is determined by a whole range of genetic and environmental factors. Single nucleotide polymorphisms (SNPs) in muscle myostatin (MSTN) and creatine kinase (CKM) genes are candidates for VO2max and skeletal muscle performance phenotypes. Common MSTN (rs3791783, rs11681628 and rs7570532) and CKM (rs344816, rs10410448, rs432979, rs1133190, rs7260359, rs7260463 and rs4884) SNPs, selected from HapMap CEU data in order to tag the genetic variability of the proteins, were genotyped in 316 male Caucasian elite endurance athletes and 304 sedentary controls from the Genathlete study. Association with elite endurance performance was determined by logistic regression analysis. The P-value for statistical significance was set at <0.01. None of the SNPs or haplotypes showed a significant association with elite endurance status. We conclude that common variants of MSTN and CKM genes do not play a role in attaining high-level endurance performance in Caucasian populations. Verf.-Referat |
| abstract_lang |
eng |
| abstract_type |
abstract |
| author2 |
Doering, F. Onur, S. Kürbitz, C. Boulay, M.R. Perusse, L. Rankinen, T. Rauramaa, R. Wolfarth, Bernd Bouchard, C. |
| author_facet |
Doering, F. Onur, S. Kürbitz, C. Boulay, M.R. Perusse, L. Rankinen, T. Rauramaa, R. Wolfarth, Bernd Bouchard, C. |
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Autor Autor Autor Autor Autor Autor Autor Autor Autor |
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P24250 |
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Doering, F. Onur, S. Kürbitz, C. Boulay, M.R. Perusse, L. Rankinen, T. Rauramaa, R. Wolfarth, Bernd Bouchard, C. |
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|
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0/Autor/ 1/Autor/Doering, F./ 0/Autor/ 1/Autor/Onur, S./ 0/Autor/ 1/Autor/Kürbitz, C./ 0/Autor/ 1/Autor/Boulay, M.R./ 0/Autor/ 1/Autor/Perusse, L./ 0/Autor/ 1/Autor/Rankinen, T./ 0/Autor/ 1/Autor/Rauramaa, R./ 0/Autor/ 1/Autor/Wolfarth, Bernd/ 0/Autor/ 1/Autor/Bouchard, C./ |
| doi |
10.1111/j.1600-0838.2010.01131.x |
| spelling |
10.1111/j.1600-0838.2010.01131.x 0905-7188 1600-0838 SMSSEO 1077418-x Ausdauerleistung Kreatin Myostatin Sauerstoffaufnahme Skelettmuskulatur Sportmedizin creatine endurance performance myostatin oxygen uptake skeletal muscles sports medicine Medizin Geschichte der Medizin Untersuchung, sportmedizinische Wasserdampf Muskulatur Skelettmuskel Muskel Sauerstoffaufnahme, relative Sauerstoffverbrauch oxygen intake oxygen consumption Single nucleotide polymorphisms in the myostatin (MSTN) and muscle creatine kinase (CKM) genes are not associated with elite endurance performance PU201107005980 201107005980 |
| url |
https://dx.doi.org/10.1111/j.1600-0838.2010.01131.x |
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fulltext |
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0 |
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0905-7188 1600-0838 |
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SMSSEO |
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1077418-x |
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0/Großbritannien/ 1/Großbritannien/England/ |
| topic |
Ausdauerleistung Kreatin Myostatin Sauerstoffaufnahme Skelettmuskulatur Sportmedizin |
| topic_facet |
Ausdauerleistung Kreatin Myostatin Sauerstoffaufnahme Skelettmuskulatur Sportmedizin |
| topic_en |
creatine endurance performance myostatin oxygen uptake skeletal muscles sports medicine |
| topic_en_facet |
creatine endurance performance myostatin oxygen uptake skeletal muscles sports medicine |
| synonym |
Medizin Geschichte der Medizin Untersuchung, sportmedizinische Wasserdampf Muskulatur Skelettmuskel Muskel Sauerstoffaufnahme, relative Sauerstoffverbrauch |
| synonym_en |
oxygen intake oxygen consumption |
| journal_facet |
Scandinavian journal of medicine & science in sports |
| container_title |
Scandinavian journal of medicine & science in sports |
| container_volume |
21 |
| container_issue |
6 |
| container_start_page |
S. 841-845 |
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1 |
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BISp |
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JO00000001282 |
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2011 |
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6 |
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