Buchumschlag

Single nucleotide polymorphisms in the myostatin (MSTN) and muscle creatine kinase (CKM) genes are not associated with elite endurance performance

Gespeichert in:
Bibliographische Detailangaben
Deutscher übersetzter Titel:Einzelne Nukleotidpolymorphien in den Myostatin- (MSTN) und Muskelkreatinkinase- (CKM)Genen stehen nicht in Zusammenhang mit Spitzenausdauerleistung
Autor:Doering, F.; Onur, S.; Kürbitz, C.; Boulay, M.R.; Perusse, L.; Rankinen, T.; Rauramaa, R.; Wolfarth, Bernd; Bouchard, C.
Erschienen in:Scandinavian journal of medicine & science in sports
Veröffentlicht:21 (2011), 6, S. 841-845, Lit.
Format: Literatur (SPOLIT)
Publikationstyp: Zeitschriftenartikel
Medienart: Gedruckte Ressource Elektronische Ressource (online)
Sprache:Englisch
ISSN:0905-7188, 1600-0838
DOI:10.1111/j.1600-0838.2010.01131.x
Schlagworte:
Ausdauerleistung
Kreatin
Myostatin
Sauerstoffaufnahme
Skelettmuskulatur
Sportmedizin
Online Zugang:
Volltext
Verfügbarkeit
Erfassungsnummer:PU201107005980
Quelle:BISp
TY  - JOUR
AU  - Doering, F.
A2  - Doering, F.
A2  - Onur, S.
A2  - Kürbitz, C.
A2  - Boulay, M.R.
A2  - Perusse, L.
A2  - Rankinen, T.
A2  - Rauramaa, R.
A2  - Wolfarth, Bernd
A2  - Bouchard, C.
DB  - BISp
DP  - BISp
KW  - Ausdauerleistung
KW  - Kreatin
KW  - Myostatin
KW  - Sauerstoffaufnahme
KW  - Skelettmuskulatur
KW  - Sportmedizin
LA  - eng
TI  - Single nucleotide polymorphisms in the myostatin (MSTN) and muscle creatine kinase (CKM) genes are not associated with elite endurance performance
TT  - Einzelne Nukleotidpolymorphien in den Myostatin- (MSTN) und Muskelkreatinkinase- (CKM)Genen stehen nicht in Zusammenhang mit Spitzenausdauerleistung
PY  - 2011
N2  - Maximal oxygen uptake (VO2max) is one of the most important determinants of elite endurance performance. VO2max is determined by a whole range of genetic and environmental factors. Single nucleotide polymorphisms (SNPs) in muscle myostatin (MSTN) and creatine kinase (CKM) genes are candidates for VO2max and skeletal muscle performance phenotypes. Common MSTN (rs3791783, rs11681628 and rs7570532) and CKM (rs344816, rs10410448, rs432979, rs1133190, rs7260359, rs7260463 and rs4884) SNPs, selected from HapMap CEU data in order to tag the genetic variability of the proteins, were genotyped in 316 male Caucasian elite endurance athletes and 304 sedentary controls from the Genathlete study. Association with elite endurance performance was determined by logistic regression analysis. The P-value for statistical significance was set at <0.01. None of the SNPs or haplotypes showed a significant association with elite endurance status. We conclude that common variants of MSTN and CKM genes do not play a role in attaining high-level endurance performance in Caucasian populations. Verf.-Referat
L2  - https://dx.doi.org/10.1111/j.1600-0838.2010.01131.x
DO  - 10.1111/j.1600-0838.2010.01131.x
SP  - S. 841-845
SN  - 0905-7188
JO  - Scandinavian journal of medicine & science in sports
IS  - 6
VL  - 21
M3  - Gedruckte Ressource
M3  - Elektronische Ressource (online)
ID  - PU201107005980
ER  -

Ähnliche Einträge