Effects of maximal exercise on blood leukocyte counts and neutrophil activity in athletes
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Deutscher übersetzter Titel: | Auswirkungen maximaler koerperlicher Belastung auf die Leukozytenzahl und die Aktivitaet der Neutrophilen im Blut von Sportlern |
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Autor: | Suzuki, K.; Sato, H.; Endo, T.; Hasegawa, H.; Mochizuki, M.; Nakaji, S.; Sugawara, K.; Totsuka, M.; Sato, K. |
Erschienen in: | Japanese journal of physical fitness and sports medicine |
Veröffentlicht: | 45 (1996), 4, S. 451-460, Lit. |
Format: | Literatur (SPOLIT) |
Publikationstyp: | Zeitschriftenartikel |
Medienart: | Gedruckte Ressource |
Sprache: | Japanisch |
ISSN: | 0039-906X, 1881-4751 |
Schlagworte: | |
Online Zugang: | |
Erfassungsnummer: | PU199705204837 |
Quelle: | BISp |
TY - JOUR AU - Suzuki, K. A2 - Suzuki, K. A2 - Sato, H. A2 - Endo, T. A2 - Hasegawa, H. A2 - Mochizuki, M. A2 - Nakaji, S. A2 - Sugawara, K. A2 - Totsuka, M. A2 - Sato, K. DB - BISp DP - BISp KW - Ausdauersport KW - Belastung, erschöpfende KW - Differentialblutbild KW - Granulozyt, neutrophiler KW - Immunologie KW - Immunsystem KW - Killerzelle KW - Leukozytenzahl KW - Leukozytose KW - Monozyt KW - Sportmedizin KW - Stress, oxidativer LA - jpn TI - Effects of maximal exercise on blood leukocyte counts and neutrophil activity in athletes TT - Auswirkungen maximaler koerperlicher Belastung auf die Leukozytenzahl und die Aktivitaet der Neutrophilen im Blut von Sportlern PY - 1996 N2 - Twenty endurance-trained athletes (five male speed-skaters, eleven male and four female cross-country skiers, 16 to 18 years) ran on a treadmill by a protocol of incremental graded increase in workload until exhaustion during an endurance training period in off-season summer. Immediately after exercise, all developed peripheral leukocytosis (1.9 times; p<0.01) due mainly to lymphocytosis (2.6 times; p<0.01) with a predominant effect on large granular lymphocyte (natural killer cell) count (5.9 times; p<0.01). Monocyte count was also enhanced 2.3 times. These increases were transitory and returned to the pre-exercise levels 1 h later. Peripheral neutrophilia was also observed by 43% immediately after exercise and remained elevated by 25% 1 h after exercise, but a shift to the left did not take place. The capacity of isolated neutrophils to produce reactive oxygen species was assessed by luminol-dependent chemiluminescence which detects mainly myeloperoxidase (MPO)- mediated formation of such hyperreactive oxidants as HOCI. The maximum intensity of chemiluminescence (peak height) upon stimulation with opsonized zymosan was significantly enhanced following exercise. Similar results were obtained when phorbol myristate acetate was employed as nonphagocytic soluble stimulus, suggesting that the capacity of neutrophils to degranulate MPO rather than phagocytosis was enhanced following exercise. In addition, the enhancements of chemiluminescence were positively correlated with the increase in segmented neutrophil count. These data indicate that maximal exercise not only mobilized mature neutrophils from the marginated pool into the circulation, but also augmented their capacity to generate reactive oxygen species of higher reactivity. Verf.-Referat SP - S. 451-460 SN - 0039-906X JO - Japanese journal of physical fitness and sports medicine IS - 4 VL - 45 M3 - Gedruckte Ressource ID - PU199705204837 ER -