The efficacy of the Nebuhaler method of administration of terbutaline sulphate in the prevention and amelioration of exercise induced asthma
| Deutscher übersetzter Titel: | Die Wirksamkeit der Nebuhaler-Methode als Applikationsform von Terbutalinsulphat in der Praevention und Behandlung des belastungsinduzierten Asthmas |
|---|---|
| Autor: | Morton, Alan R.; Papalia, Shona M.; Morton, Peter S.; Fitch, Kenneth D. |
| Erschienen in: | Australian journal of science & medicine in sport |
| Veröffentlicht: | 24 (1992), 4, S. 103-106, Lit. |
| Format: | Literatur (SPOLIT) |
| Publikationstyp: | Zeitschriftenartikel |
| Medienart: | Gedruckte Ressource |
| Sprache: | Englisch |
| ISSN: | 0813-6289 |
| Schlagworte: | |
| Online Zugang: | |
| Erfassungsnummer: | PU199309064576 |
| Quelle: | BISp |
Abstract
Thirteen asthmatic subjects performed eight-minute treadmill exercise tests following the administration of each of three treatments viz., placebo via Nebuhaler, terbutaline sulphate via metered dose inhaler (MDI) and terbutaline sulphate via Nebuhaler. Pulmonary function measurements of FEV1.0, PEFR, FEF25-75, and FEF50 were recorded before and after treatment, and at various times after cessation of exercise. There were no significant differences between the MDI and Nebuhaler in the response of FEV1, FEF25-75, and FEF50 to treatment or exercise. Difference in lung function between the Nebuhaler and MDI methods of administration was limited to PEFR. This occurred at 35 minutes post-exercise when MDI values were on average 7.8 higher than the Nebuhaler values at this time. Both active treatments significantly improved lung function compared to the placebo. It is concluded that when correct MDI administration techniques are employed both methods of administration of aerosol terbutaline sulphate are of equal efficacy in the prevention and amelioration of exercise-induced asthma. Verf.-Referat