TY  - JOUR
AU  - Farrell, P.A.
A2  - Farrell, P.A.
A2  - Kjær, Michael
A2  - Bach, F.W.
A2  - Galbo, H.
DB  - BISp
DP  - BISp
KW  - ACTH
KW  - Ausdauersport
KW  - Ausdauertraining
KW  - Belastung, supramaximale
KW  - Belastungsintensität
KW  - Endokrinium
KW  - Endorphine
KW  - Laufbandergometrie
KW  - Sportmedizin
KW  - Trainingswirkung
LA  - eng
TI  - Beta-endorphin and adrenocorticotropin response to supramaximal treadmill exercise in trained and untrained males
TT  - Reaktion von Beta-Endorphin und Adrenokortikotropin auf supramaximale Laufbandbelastung bei trainierten und untrainierten Maennern
PY  - 1987
N2  - The response of plasma beta-endorphin (beta-EP) and adrenocorticotropin (ACTH) was studied in seven well-trained (T) young endurance athletes and seven untrained (UT) age- and weight-matched males during treadmill exercise. Subjects ran continuously for 7 min at 60 VO2max, 3 min at 100 VO2max and 2 min at 110 VO2max. Arterialized blood was obtained periodically from a cannulated heated hand vein. Plasma beta-EP was measured by radio-immunoassay (RIA) which incorporated an antibody that did not cross-react with beta-lipotropin. Plasma beta-EP was similar between groups at rest and did not change at the 60 VO2max stage. Beta-endorphin significantly increased at 100 VO2max with both groups responding similarly. A further increase occurred at 110 VO2max (T=10.8+/-2.0 and UT = 6.6+/-1.0 fmol/ml, P < 0.05 for between group differences). This between group difference persisted 1 min after exercise when the highest beta-EP levels were reached. Plasma ACTH responses were similar to beta-EP with the highest values (T = 61.5 plus minus 7.2, UT = 45.7 plus minus 6.8 fmol/ml, P < 0.05 for between group differences) occuring at 1 min post-exercise. A positive correlation, r = 0.85, P < 0.05, was found between beta-EP and ACTH using the 1 min post-exercise values. The enhanced response of beta-EP and ACTH in T may indicate a training-induced adaptation which increases the response capacity to extreme levels of stress. Verf.-Referat
SP  - S. 619-125
SN  - 0001-6772
JO  - Acta physiologica Scandinavica
IS  - 4
VL  - 130
M3  - Gedruckte Ressource
ID  - PU198807007770
ER  -