Peripheral thermal responses in normal and cold-sensitive individuals to sublingual Glyceryl Trinitrate (GTN)
| Autor: | Hope, Katrina; Eglin, Clare M; Golden, Frank; Tipton, Michael J |
|---|---|
| Sprache: | Englisch |
| Veröffentlicht: |
2015 |
| Quelle: | University of Portsmouth: Portsmouth Research Portal |
| Online Zugang: |
https://doi.org/10.1186/2046-7648-4-S1-A34 https://researchportal.port.ac.uk/portal/en/publications/peripheral-thermal-responses-in-normal-and-coldsensitive-individuals-to-sublingual-glyceryl-trinitrate-gtn(3bdaf68e-e9a7-4546-b0bc-87bdc3f6370a).html https://researchportal.port.ac.uk/ws/files/3023922/Peripheral_thermal_responses_in_normal.pdf http://www.extremephysiolmed.com/content/4/S1/A34 |
| Erfassungsnummer: | ftunivportsmpubl:oai:researchportal.port.ac.uk:publications/3bdaf68e-e9a7-4546-b0bc-87bdc3f6370a |
Zusammenfassung
Non-freezing cold injury (NFCI) is caused by prolonged exposure of the extremities to cold. The long-term sequelae of NFCI, include cold-sensitivity and pain[1]. The cold sensitivity is characterised by a reduction in basal skin blood flow and augmented vasoconstriction during cold exposure. We tested the hypothesis that sublingual GTN would increase blood flow in the peripheral microcirculation during and after a mild cold challenge in individuals who had not been diagnosed with NFCI, but were cold-sensitive.