Poor Lower Extremity Functioning Is Associated with Modest Increased Incidence of Probable Dementia
| Autor: | Sergio L. Teruya; Cara Dimino; Kevin D. Silverman; Thelma Mielenz |
|---|---|
| Sprache: | Englisch |
| Veröffentlicht: |
2021 |
| Quelle: | MDPI Open Access Publishing |
| Online Zugang: |
https://dx.doi.org/10.3390/geriatrics6030077 https://doi.org/10.3390/geriatrics6030077 |
| Erfassungsnummer: | ftmdpi:oai:mdpi.com:/2308-3417/6/3/77/ |
| id |
ftmdpi:oai:mdpi.com:/2308-3417/6/3/77/ |
|---|---|
| bisp-collection |
base |
| recordtype |
bispbase |
| url |
https://dx.doi.org/10.3390/geriatrics6030077 https://doi.org/10.3390/geriatrics6030077 |
| url-type |
primary info |
| spelling |
aging physical functioning Short Physical Performance Battery cognitive function Poor Lower Extremity Functioning Is Associated with Modest Increased Incidence of Probable Dementia |
| publishDate |
2021 |
| publishDate_facet |
2021 |
| baseCollectionName |
MDPI Open Access Publishing |
| baseCountry |
ch |
| title |
Poor Lower Extremity Functioning Is Associated with Modest Increased Incidence of Probable Dementia |
| spellingShingle |
Poor Lower Extremity Functioning Is Associated with Modest Increased Incidence of Probable Dementia |
| title_short |
Poor Lower Extremity Functioning Is Associated with Modest Increased Incidence of Probable Dementia |
| title_sort |
Poor Lower Extremity Functioning Is Associated with Modest Increased Incidence of Probable Dementia |
| author2 |
Sergio L. Teruya Cara Dimino Kevin D. Silverman Thelma Mielenz |
| author_facet |
Sergio L. Teruya Cara Dimino Kevin D. Silverman Thelma Mielenz |
| author2-role |
Autor Autor Autor Autor |
| abstract |
Lower extremity functioning in older adults provides a measure of poor physical performance and can predict negative health outcomes. The consequences of reduced lower extremity functioning on cognitive decline, measured as time-varying variables, have not been well documented in previous studies. We aimed to evaluate whether lower extremity functioning is associated with an increased incidence rate of probable dementia among older adults using data from the National Health and Aging Trends Study (NHATS). Participants (n = 6457) were followed for 8 years to examine the relationship between lower extremity functioning, as measured by the Short Physical Performance Battery (SPPB), and incident probable dementia. Using weighted data, a multivariable Poisson regression with generalized estimating equations (GEE) was used to calculate incidence rate ratios (IRR), adjusting for covariates and clustering. Participants with low SPPB scores (0–5) had a 5% increase in incident probable dementia when compared with those who had good SPPB scores (10–12) in the adjusted model (IRR = 1.05; 95% CI = 1.04–1.07). Lower extremity functioning is associated with a modest increase in incident probable dementia. The SPPB score may be helpful in identifying subjects at risk of dementia. Efforts aimed at improving physical functioning may lead to better cognitive outcomes. |
| abstract_type |
general |
| abstract_lang |
eng |
| language |
eng |
| publisher |
Multidisciplinary Digital Publishing Institute |
| _version_ |
1793497050390724608 |
| score |
13,561537 |