Exercise and Protein Intake: A Synergistic Approach against Sarcopenia
Autor: | Anna Maria Martone; Emanuele Marzetti; Riccardo Calvani; Anna Picca; Matteo Tosato; Luca Santoro; Angela Di Giorgio; Antonio Nesci; Alex Sisto; Angelo Santoliquido; Francesco Landi |
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Sprache: | Englisch |
Veröffentlicht: |
2017 |
Quelle: | Directory of Open Access Journals: DOAJ Articles |
Online Zugang: |
http://dx.doi.org/10.1155/2017/2672435 https://doaj.org/toc/2314-6133 https://doaj.org/toc/2314-6141 2314-6133 2314-6141 doi:10.1155/2017/2672435 https://doaj.org/article/d57583f0ae8a484a895f00a630e9b07e https://doi.org/10.1155/2017/2672435 https://doaj.org/article/d57583f0ae8a484a895f00a630e9b07e |
Erfassungsnummer: | ftdoajarticles:oai:doaj.org/article:d57583f0ae8a484a895f00a630e9b07e |
Zusammenfassung
Sarcopenia, the age-dependent loss of muscle mass and function/strength, is increasingly recognized as a major risk factor for adverse outcomes in frail older people. As such, the skeletal muscle is a relevant target for interventions aimed at preventing or postponing the occurrence of negative health-related events in late life. The association among physical inactivity, insufficient intake of energy and protein, and poor muscle health in older adults suggests that physical exercise and targeted nutritional supplementation may offer substantial therapeutic gain against sarcopenia and its negative correlates. This view is supported by observational studies as well as by small-scale clinical trials. In this review, we summarize the available evidence on the beneficial effects of behavioral interventions on sarcopenia. We also briefly describe how the knowledge gathered so far has been used to design the “Sarcopenia and Physical fRailty IN older people: multicomponenT Treatment strategies” (SPRINTT) project. The randomized clinical trial conducted within SPRINTT will provide robust evidence on the effectiveness of exercise and nutrition at preventing negative outcomes associated with sarcopenia and physical frailty.