Influencing factors for dynamic changes in the severity of fatty liver in patients with acute pancreatitis and fatty liver

Autor: CHEN Qiang
Sprache: Chinesisch
Veröffentlicht: 2023
Quelle: Directory of Open Access Journals: DOAJ Articles
Online Zugang: http://www.lcgdbzz.org/cn/article/doi/10.3969/j.issn.1001-5256.2023.06.018
https://doaj.org/toc/1001-5256
1001-5256
https://doaj.org/article/3f6e530851b44f18b533e6a96f1691aa
https://doaj.org/article/3f6e530851b44f18b533e6a96f1691aa
Erfassungsnummer: ftdoajarticles:oai:doaj.org/article:3f6e530851b44f18b533e6a96f1691aa

Zusammenfassung

ObjectiveTo investigate the dynamic change of fatty liver (FL) in patients with fatty liver-related acute pancreatitis (FLAP) and related influencing factors. MethodsA total of 136 FLAP patients who were admitted to The First Affiliated Hospital of Baotou Medical College, Inner Mongolia University of Science and Technology, from December 2017 to December 2021 were enrolled as subjects. With the first CT examination after admission as the starting point and the last CT examination before discharge as the ending point, the subjects were divided into FL aggravation group (FLAG group), FL mild mitigation group (FLMMG group), and FL significant mitigation group (FLSMG group) according to the degree of change in FL. General information and clinical data were compared between groups. General information included age, sex, length of hospital stay, etiology of acute pancreatitis (AP), and changes in body weight and temperature, and clinical data included treatment modality and the changes in laboratory markers and AP severity. The chi-square test or the Fisher’s exact test was used for comparison of categorical data between groups. A one-way analysis of variance was used for comparison of normally distributed continuous data between multiple groups, and the least significant difference t-test was used for further comparison between two groups; the Kruskal-Wallis H test was used for comparison of non-normally distributed continuous data between multiple groups, and the Mann-Whitney U test with Bonferroni correction was used for further comparison between two groups. Dynamic changes of data were expressed as the difference from the starting point to the ending point, and a covariance analysis was used for comparison of data with dynamic changes. The Spearman correlation analysis was used to investigate the correlation of indices with significant changes with the degree of change in FL. ResultsAmong the 136 FLAP patients, 61 achieved mild mitigation of FL, 59 achieved significant mitigation of FL, and 16 experienced ...