Stabilization of body balance with LightTouch following a mechanical perturbation : adaption of sway and disruption of right posterior parietal cortex by cTBS

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Bibliographische Detailangaben
Deutscher übersetzter Titel:Stabilisierung des Körpergleichgewichts mittels LightTouch nach einer mechanischen Perturbation : Adaption bei Schwanken und Störung des rechten posterioren parietalen Cortex durch cTBS
Autor:Kaulmann, David; Saveriano, Matteo; Lee, Dongheui; Hermsdörfer, Joachim; Johannsen, Leif
Erschienen in:PLoS one / Public Library of Science
Veröffentlicht:15 (2020), 7, Art.-ID e0233988, [20 S.], Lit.
Format: Literatur (SPOLIT)
Publikationstyp: Zeitschriftenartikel
Medienart: Elektronische Ressource (online)
Sprache:Englisch
ISSN:1932-6203
DOI:10.1371/journal.pone.0233988
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Erfassungsnummer:PU202104002997
Quelle:BISp

Abstract des Autors

Light touch with an earth-fixed reference point improves balance during quite standing. In our current study, we implemented a paradigm to assess the effects of disrupting the right posterior parietal cortex on dynamic stabilization of body sway with and without Light Touch after a graded, unpredictable mechanical perturbation. We hypothesized that the benefit of Light Touch would be amplified in the more dynamic context of an external perturbation, reducing body sway and muscle activations before, at and after a perturbation. Furthermore, we expected sway stabilization would be impaired following disruption of the right Posterior Parietal Cortex as a result of increased postural stiffness. Thirteen young adults stood blindfolded in Tandem-Romberg stance on a force plate and were required either to keep light fingertip contact to an earth-fixed reference point or to stand without fingertip contact. During every trial, a robotic arm pushed a participant’s right shoulder in medio-lateral direction. The testing consisted of 4 blocks before TMS stimulation and 8 blocks after, which alternated between Light Touch and No Touch conditions. In summary, we found a strong effect of Light Touch, which resulted in improved stability following a perturbation. Light Touch decreased the immediate sway response, steady state sway following re-stabilization, as well as muscle activity of the Tibialis Anterior. Furthermore, we saw gradual decrease of muscle activity over time, which indicates an adaptive process following exposure to repetitive trials of perturbations. We were not able to confirm our hypothesis that disruption of the rPPC leads to increased postural stiffness. However, after disruption of the rPPC, muscle activity of the Tibialis Anterior is decreased more compared to sham. We conclude that rPPC disruption enhanced the intra-session adaptation to the disturbing effects of the perturbation.