Abstract des Autors

Neurotransmitters govern the communication between neurons in different brain regions and neuronal pathways. Generally speaking, nerve cells in the brain are firing all the time, giving a massive ‘background noise’. Probably none of the neurons in the brain are exposed only to excitation, and certainly no nerve cells are affected solely by inhibitory signals. Most brain functions such as learning, memory, cognition, control of movement and other mechanisms need the interaction of neurotransmitters and neuromodulators. In order to establish new memories and to encode, store and retrieve memories, cross-talk between several brain structures such as the hippocampus and interplay between several neurotransmitters and neuromodulators are important. Understanding the function of various neurotransmitters and neuromodulators helps in understanding their role during whole-body exercise, fatigue, learning and memory. (geändert)