Football training in men with prostate cancer undergoing androgen deprivation therapy : activity profile and short-term skeletal and postural balance adaptations
Deutscher übersetzter Titel: | Fußballtraining bei Männern mit Prostatakrebs während der antiandrogenen Therapie : Aktivitätsprofil und kurzfristige skelettale und gleichgewichtsbezogene Anpassungen |
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Autor: | Uth, Jacob; Hornstrup, Therese; Christensen, Jesper F.; Christensen, Karl B.; Jørgensen, Niklas R.; Helge, Eva W.; Schmidt, Jakob F.; Brasso, Klaus; Helge, Jørn Wulff; Jakobsen, Markus D.; Andersen, Lars L.; Rørth, Mikael; Midtgaard, Julie; Krustrup, Peter |
Erschienen in: | European journal of applied physiology |
Veröffentlicht: | 116 (2016), 3, S. 471-480, Lit. |
Format: | Literatur (SPOLIT) |
Publikationstyp: | Zeitschriftenartikel |
Medienart: | Elektronische Ressource (online) Gedruckte Ressource |
Sprache: | Englisch |
ISSN: | 1439-6319, 0301-5548 |
DOI: | 10.1007/s00421-015-3301-y |
Schlagworte: | |
Online Zugang: | |
Erfassungsnummer: | PU201703002143 |
Quelle: | BISp |
Abstract des Autors
Purpose: to investigate the activity profile of football training and its short-term effects on bone mass, bone turnover markers (BTMs) and postural balance in men with prostate cancer (PCa) undergoing androgen deprivation therapy (ADT). Methods: This was a randomised 12-week study in which men with PCa undergoing ADT were assigned to a football intervention group [FTG, n = 29, 67 ± 7 (±SD) years] training 2‒3 times per week for 45‒60 min or to a control group (n = 28, 66 ± 5 years). The activity profile was measured using a 5-Hz GPS. The outcomes were total body and leg bone mineral content (BMC) and density, BTMs and postural balance. Results: In the last part of the 12 weeks, FTG performed 194 ± 41 accelerations and 296 ± 65 decelerations at >0.6 m/s/s and covered a distance of 905 ± 297 m at speeds >6 km/h and 2646 ± 705 m per training session. Analysis of baseline-to-12-week change scores showed between-group differences in favour of FTG in total body BMC [26.4 g, 95 % confidence interval (CI): 5.8–46.9 g, p = 0.013], leg BMC (13.8 g, 95 % CI: 7.0‒20.5 g, p < 0.001) and markers of bone formation: P1NP (36.6 µg/L, 95 % CI: 10.4‒62.8 µg/L, p = 0.008) and osteocalcin (8.6 µg/L, 95 % CI: 3.3‒13.8 µg/L, p < 0.01). The number of decelerations correlated to the increase in leg BMC (r = 0.65, p = 0.012). No between-group differences were observed for the remaining outcomes. Conclusion: Football training involves numerous runs, accelerations and decelerations, which may be linked to marked increases in bone formation markers and preserved bone mass in middle-aged and elderly men with PCa undergoing ADT.