Effects of pre-exercise alkalosis on the decrease in VO2 at the end of all-out exercise

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Deutscher übersetzter Titel:Auswirkungen einer vor der Belastung bestehenden Alkalose auf den VO2-Rückgang am Ende einer Ausbelastung
Autor:Thomas, Claire; Delfour-Peyrethon, Rémi; Bishop, David J.; Perrey, Stéphane; Leprêtre, Pierre-Marie; Dorel, Sylvain; Hanon, Christine
Erschienen in:European journal of applied physiology
Veröffentlicht:116 (2016), 1, S. 85-95, Lit.
Format: Literatur (SPOLIT)
Publikationstyp: Zeitschriftenartikel
Medienart: Elektronische Ressource (online) Gedruckte Ressource
Sprache:Englisch
ISSN:1439-6319, 0301-5548
DOI:10.1007/s00421-015-3239-0
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Erfassungsnummer:PU201703001869
Quelle:BISp

Abstract des Autors

Purpose: This study determined the effects of pre-exercise sodium bicarbonate ingestion (ALK) on changes in oxygen uptake (V˙O2) at the end of a supramaximal exercise test (SXT). Methods: Eleven well-trained cyclists completed a 70-s all-out cycling effort, in double-blind trials, after oral ingestion of either 0.3 g kg−1 of sodium bicarbonate (NaHCO3) or 0.2 g kg−1 body mass of calcium carbonate (PLA). Blood samples were taken to assess changes in acid–base balance before the start of the supramaximal exercise, and 0, 5 and 8 min after the exercise; ventilatory parameters were also measured at rest and during the SXT. Results: At the end of the PLA trial, which induced mild acidosis (blood pH = 7.20), subjects presented a significant decrease in V˙O2 (P < 0.05), which was related to the amplitude of the decrease in minute ventilation (V˙E) during the SXT (r = 0.70, P < 0.01, n = 11). Pre-exercise metabolic alkalosis significantly prevented the exercise-induced decrease in V˙O2 in eleven well-trained participants (PLA: 12.5 ± 2.1 % and ALK: 4.9 ± 0.9 %, P < 0.05) and the decrease in mean power output was significantly less pronounced in ALK (P < 0.05). Changes in the V˙O2 decrease between PLA and ALK trials were positively related to changes in the V˙E decrease (r = 0.74, P < 0.001), but not to changes in power output (P > 0.05). Conclusions: Pre-exercise alkalosis counteracted the V˙O2 decrease related to mild acidosis, potentially as a result of changes in V˙E and in muscle acid–base status during the all-out supramaximal exercise.