The association between MCT1 T1470A polymorphism and power-oriented athletic performance

Gespeichert in:
Bibliographische Detailangaben
Deutscher übersetzter Titel:Die Verbindung zwischen dem MCT1 T1470A Polymorphismus und schnellkraftbetonter sportlicher Leistungsfähigkeit
Autor:Kikuchi, Naoki; Fuku, Noriyuki; Matsumoto, Ryutaro; Matsumoto, Shingo; Murakami, Haruka; Miyachi, Motohiko; Nakazato, Koichi
Erschienen in:International journal of sports medicine
Veröffentlicht:38 (2017), 1, S. 76-80, Lit.
Format: Literatur (SPOLIT)
Publikationstyp: Zeitschriftenartikel
Medienart: Elektronische Ressource (online) Gedruckte Ressource
Sprache:Englisch
ISSN:0172-4622, 1439-3964
DOI:10.1055/s-0042-117113
Schlagworte:
Online Zugang:
Erfassungsnummer:PU201701000851
Quelle:BISp

Abstract des Autors

The purpose of this study was to investigate the effects of the MCT1 T1470A polymorphism (rs1049434) on power-oriented performance and lactate concentration during or after cycling sprints in Japanese wrestlers. Participants (199 wrestlers and 649 controls) were genotyped for the MCT1 T1470A genotype (rs1049434) using the TaqMan® Assay. All wrestlers were international (n=77) or national (n=122) level athletes. Among them, 46 wrestlers performed 2 anaerobic performance tests, a 30-s Wingate Anaerobic test (WAnT) and a series of 10 maximal effort 10-s sprints on a cycle ergometer. Blood lactate levels were measured before, during, and after the tests. In the A-allele recessive model (AA vs. TA+TT), the frequency of the AA genotype was significantly higher in all wrestlers than in controls (p=0.037). Wrestlers with AA genotype had lower blood lactate concentrations than those with TA+TT genotype at 10 min after the WAnT and following the 5th and the final set of repeated cycling sprints (p<0.05). The AA genotype of the MCT1 T1470A polymorphism is over-represented in wrestlers compared with controls and is associated with lower blood lactate concentrations after 30-s WAnT and during intermittent sprint tests in Japanese wrestlers.