Fast screening for liposome encapsulated hemoglobin (LEH) using ADVIA 120 flow cytometry-based hematological analyzer
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| Deutscher übersetzter Titel: | Schnelle Screeningverfahren für liposomenverkapseltes Hämoglobin (LEH) mit dem Hämatologiesystem ADVIA 120 |
|---|---|
| Autor: | Donati, F.; Torre, X. de la; Botrè, F. |
| Erschienen in: | Recent advances in doping analysis (21) : Proceedings of the Manfred-Donike-Workshop ; 31th Cologne Workshop on Dope Analysis ; 24th February to 1st March 2013 |
| Veröffentlicht: | Köln: Sportverl. Strauß (Verlag), 2013, S. 161-163, Lit. |
| Format: | Literatur (SPOLIT) |
| Publikationstyp: | Sammelwerksbeitrag |
| Medienart: | Elektronische Ressource (Datenträger) |
| Sprache: | Englisch |
| Schlagworte: | |
| Online Zugang: | |
| Erfassungsnummer: | PU201408007439 |
| Quelle: | BISp |
Abstract
The artificial enhancing of the uptake, transport or delivery of oxygen, including the intake of modified hemoglobin products (e.g HBOCs) is a prohibited method included in the WADA List of Prohibited Substances (Ml. Manipulation of blood and blood components). In this work we present a fast screening to detect liposome encapsulated hemoglobins (LEH). LEH can be detected in serum/plasma using flow cytometry-based techniques with a dual color staining procedure that requires several hours for sample preparation and analysis. The aim of this work is to test the potential of a cytometry-based hematological analyzer such as ADVIA 120 (Siemens) for a rapid screening of the presence of liposomes within a serum/plasma sample. Verf.-Referat