A randomized trial of aerobic versus resistance exercise in prostate cancer survivors
Deutscher übersetzter Titel: | Eine randomisierte Untersuchung von Ausdauer- versus Krafttraining bei Prostatakrebs-Überlebenden |
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Autor: | Santa Mina, Daniel; Alibhai, Shabbir M.H.; Matthew, Andrew G.; Guglietti, Crissa L.; Pirbaglou, Meysam; Trachtenberg, John; Ritvo, Paul G. |
Erschienen in: | Journal of aging and physical activity |
Veröffentlicht: | 21 (2013), 4, S. 455-478, Lit. |
Format: | Literatur (SPOLIT) |
Publikationstyp: | Zeitschriftenartikel |
Medienart: | Gedruckte Ressource Elektronische Ressource (online) |
Sprache: | Englisch |
ISSN: | 1063-8652, 1543-267X |
DOI: | 10.1123/japa.21.4.455 |
Schlagworte: | |
Online Zugang: | |
Erfassungsnummer: | PU201401000335 |
Quelle: | BISp |
Abstract des Autors
Androgen-deprivation therapy (ADT) for prostate cancer (PCa) has side effects that significantly impair health-related quality of life (HRQOL). Exercise ameliorates many side effects of ADT, but different modalities, particularly in the home-based setting, have not been well studied. In this study the authors randomly assigned 66 PCa survivors receiving ADT to 6 mo of home-based aerobic or resistance training. Psychosocial well-being and physical fitness were measured at baseline, 3 and 6 mo, and then 6 mo postintervention. Intention-to-treat analyses showed that fatigue and HRQOL were not significantly different between groups; however, in a per-protocol analysis the resistance-exercise training group demonstrated clinically significant improvements in HRQOL. Differential within-group effects on physical fitness were also observed at various time points. At all time points, the aerobic-training group engaged in significantly more physical activity than the resistance-training group, a finding that should be further examined given evidence-based guidelines for activity volume in cancer survivors. Verf.-Referat