Effect of aerobic exercise on insulin, insulin-like growth factor-1 and insulin-like growth factor binding protein-3 in overweight and obese postmenopausal women
Gespeichert in:
| Deutscher übersetzter Titel: | Auswirkung von aerobem Training auf Insulin, Insulin-ähnlichem Wachstumsfaktor-1 und Insulin-ähnlichem Wachstumsfaktor bindendes Protein-3 bei übergewichtigen und fettleibigen postmenopausalen Frauen |
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| Autor: | Wieczorek-Baranowska, A.; Nowak, A.; Michalak, E.; Karolkiewicz, J.; Pospieszna, B.; Rutkowski, R.; Laurentowska, M.; Pilaczyńska-Szcześniak, Ł. |
| Erschienen in: | The Journal of sports medicine and physical fitness |
| Veröffentlicht: | 51 (2011), 3, S. 525-532, Lit. |
| Format: | Literatur (SPOLIT) |
| Publikationstyp: | Zeitschriftenartikel |
| Medienart: | Gedruckte Ressource Elektronische Ressource (online) |
| Sprache: | Englisch |
| ISSN: | 0022-4707, 1827-1928 |
| Schlagworte: | |
| Online Zugang: | |
| Erfassungsnummer: | PU201303001553 |
| Quelle: | BISp |
Abstract des Autors
AIM: The purpose of presented study was to verify the influence of aerobic physical activity program on the serum insulin, insulin-like growth factor-1 (IGF-1) and insulin-like growth factor binding protein-3 (IGFBP-3) concentrations in overweight and obese postmenopausal women.
METHODS: Somatic parameters and serum concentrations of insulin, IGF-1 and IGFBP-3 were measured in 21 overweight and obese women, before and after 8-week cycloergometer physical workout and 16 age-matched, controls. Age of all studied women ranged from 54 to 78 years.
RESULTS: The comparative analysis of biochemical indices measured before and after the training program showed that the systematic exercise cause the significant decrease in insulin (P<0.05) and IGF-1 concentrations (P<0.05). There were no differences in these parameters in controls over the studied period. The level of IGFBP-3 was not significantly changed in both investigated groups. In women participating in the training program the positive correlation (P<0.05) between changes in IGF-1 levels (Δ) and changes in insulin concentrations (Δ) within two terms of the study were found. The magnitude of changes (Δ) in insulin and IGF-1 levels over the study period correlated with their concentrations measured before the training program (P<0.01).
CONCLUSION: Results of the present study indicate that regular aerobic physical activity decreases serum insulin and IGF-1 levels in postmenopausal women. The magnitude of insulin and IGF-1 concentration changes depend on their initial levels. Changes of IGF-1 levels are associated with insulin concentration modifications. Verf.-Referat