Variation in the HIF1a gene in elite rowers
Gespeichert in:
| Deutscher übersetzter Titel: | Variation im HIF1a-Gen von Eliteruderern |
|---|---|
| Autor: | Cięszczyk, Paweł; Kalinski, Michael; Ostanek, Magdalena; Jascaniene, Nijole; Krupecki, Krzysztof; Ficek, Krzysztof; Sawczuk, Marek; Maciejewska, Agnieszka |
| Erschienen in: | Journal of strength and conditioning research |
| Veröffentlicht: | 26 (2012), 12, S. 3270-3274, Lit. |
| Format: | Literatur (SPOLIT) |
| Publikationstyp: | Zeitschriftenartikel |
| Medienart: | Gedruckte Ressource |
| Sprache: | Englisch |
| ISSN: | 1064-8011, 1533-4287 |
| DOI: | 10.1519/JSC.0b013e31824b876d |
| Schlagworte: | |
| Online Zugang: | |
| Erfassungsnummer: | PU201302001251 |
| Quelle: | BISp |
Abstract
The transcription factor hypoxia-inducible factor 1 (HIF1) is one of the key regulators of cellular metabolism. The aim of this study was to analyze the possible importance of the HIF1A Pro582Ser polymorphisms in rowing. One hundred twenty-seven male Polish rowers (both former and current competitors) were recruited for this study. Genotyping was carried out by polymerase chain reaction. Significance was assessed by Chi-square (χ2) analysis. The results obtained revealed that frequency of the HIF1A Pro/Ser genotype (32.28 vs. 18.91%; p = 0.006) and Ser allele (16.93 vs. 10.00%; p = 0.01) were significantly higher in the rowers compared with those in controls. The results obtained confirm the significance of the HIF1A gene as a useful genetic marker in rowing. This kind of information would presumably be applicable in a program to search for the most predisposed individuals and also in the planning of training programs. Verf.-Referat