A rapid ultra-performance liquid chromatography (UPLCTM)/mass spectrometry : applications in doping control
Gespeichert in:
| Deutscher übersetzter Titel: | Eine schnelle Ultra-Performance Flüssigkeits-Chromatographie (UPLCTM)/Massenspektrometrie : die Anwendung in der Dopinanalytik |
|---|---|
| Autor: | Okano, Masato; Sato, Mitsuhiko; Ikekita, Ayako; Kageyama, Shinji |
| Erschienen in: | Recent advances in doping analysis (15) : Proceedings of the Manfred Donike Workshop ; 25th Cologne Workshop on Dope Analysis ; 25th February to 2nd March 2007 |
| Veröffentlicht: | Köln: Sportverl. Strauß (Verlag), 2007, S. 359-362, Lit. |
| Format: | Literatur (SPOLIT) |
| Publikationstyp: | Sammelwerksbeitrag |
| Medienart: | Elektronische Ressource (online) Gedruckte Ressource |
| Sprache: | Englisch |
| Schlagworte: | |
| Online Zugang: | |
| Erfassungsnummer: | PU201001000335 |
| Quelle: | BISp |
Abstract
Most laboratories, including our laboratory, make efforts to simplify analytical methods without increasing the number of instruments or the number of personnel. Our laboratory will aim to perform doping control tests an 750 urine samples for the 11th World Championships in Athletics Osaka 2007, within 10 days. Thus, screening procedures have to be modified to obtain the analytical results within a required period of time. Several methods have been published for the detection of diuretics and corticosteroids by means of HPLC/MS/MS. The UPLCTM has recently been used as a way to conduct a rapid throughput analysis as an alternative to traditional high-performance liquid chromatography (HPLC). In this study, the potential use of UPLCTM MS/MS for diuretics, masking agents, stimulants and corticosteroids in our laboratory were described. Einleitung (geändert)