Myosin heavy chain isoform expression: influence on isoinertial and isometric performance
Deutscher übersetzter Titel: | Expression von Isoformen der Myosin-Schwerkette: Einfluss auf isoinertiale und isometrische Leistung |
---|---|
Autor: | Schilling, Brian K.; Fry, Andrew C.; Weiss, Lawrence W.; Chiu, Loren Z.F. |
Erschienen in: | Research in sports medicine |
Veröffentlicht: | 13 (2005), 4, S. 301-315, Lit. |
Format: | Literatur (SPOLIT) |
Publikationstyp: | Zeitschriftenartikel |
Medienart: | Gedruckte Ressource Elektronische Ressource (online) |
Sprache: | Englisch |
ISSN: | 1543-8627, 1543-8635 |
DOI: | 10.1080/15438620500359786 |
Schlagworte: | |
Online Zugang: | |
Erfassungsnummer: | PU200708002122 |
Quelle: | BISp |
Abstract des Autors
Thirty-six healthy men with varying degrees of physical training background performed maximal-effort isometric and isoinertial knee extensor actions, with relative loads equal to 40% and 70% of one-repetition maximum. Force, velocity, and power were derived from force and linear position transducers at 500 Hz. Biopsies were taken from the vastus lateralis and analyzed by SDS-PAGE for relative myosin heavy chain (MHC) content. Relative MHC IIx content was included in a regression model, and explained variance noted. Relative MHC I content was subsequently added to the regression model to determine what, if any, additional variance was explained beyond that of MHC IIx. Results indicated that no relationship (r = 0.0 to 0.1) exists between the relative expression of MHC isoforms from the vastus lateralis and isometric/isoinertial performance in a population with diverse training backgrounds. Lack of nervous system adaptations in the untrained subjects in the study possibly attenuates the significant relationship between MHC and in-vivo muscle performance previously established in trained populations. Verf.-Referat