Exercise alters fractal dimension and spatial correlation of pulmonary blood flow in the horse
| Deutscher übersetzter Titel: | Koerperliche Belastung veraendert die Fraktaldimension und den raeumlichen Zusammenhang der Lungendurchblutung bei Pferden |
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| Autor: | Sinclair, S.E.; McKinney, S.; Glenny, R.W.; Bernard, S.L.; Hlastala, M.P. |
| Erschienen in: | Journal of applied physiology |
| Veröffentlicht: | 88 (2000), 6, S. 2269-2278, Lit. |
| Format: | Literatur (SPOLIT) |
| Publikationstyp: | Zeitschriftenartikel |
| Medienart: | Gedruckte Ressource |
| Sprache: | Englisch |
| ISSN: | 8750-7587, 0021-8987, 0161-7567, 1522-1601 |
| Schlagworte: | |
| Online Zugang: | |
| Erfassungsnummer: | PU199912500110 |
| Quelle: | BISp |
Abstract des Autors
We determined the changes in fractal dimensions and spatial correlations of regional pulmonary blood flow with increasing exercise in race horses (n=4) by using 15-micro-m fluorescent microspheres. Fluorescence was measured to quantitate regional blood to 1.3-cm**3 samples (n=1,621-2,503). Perfusion distributions were characterized with fractal dimensions (a measure of spatial variability) and spatial correlations. On average, the fractal dimension decreased with exercise (trot 1.216 to gallop 1.173; P<0.05) despite a variable fractal dimension at rest. Spatial correlation of flow to neighboring pieces increased with exercise (trot 0.57+/-0.074 to gallop 0.73+/-0.051) and was inversely correlated with fractal dimension, indicating better spatial correlation as blood flow distribution becomes more uniform. This is the first study to document a change in fractal dimension as a result of increasing pulmonary blood flow. Spatial differences in response to vasoregulatory mediators may play a role in this phenomenon. Verf.-Referat