Influence of mild exercise at the lactate threshold on glucose effectiveness
Deutscher übersetzter Titel: | Einfluss von submaximaler koerperlicher Belastung an der anaeroben Schwelle auf die Glukoseeffektivitaet |
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Autor: | Sakamoto, M.; Higaki, Y.; Nishida, Y.; Kiyonaga, A.; Shindo, M.; Tokuyama, K.; Tanaka, H. |
Erschienen in: | Journal of applied physiology |
Veröffentlicht: | 87 (1999), 6, S. 2305-2310, Lit. |
Format: | Literatur (SPOLIT) |
Publikationstyp: | Zeitschriftenartikel |
Medienart: | Gedruckte Ressource |
Sprache: | Englisch |
ISSN: | 8750-7587, 0021-8987, 0161-7567, 1522-1601 |
Schlagworte: | |
Online Zugang: | |
Erfassungsnummer: | PU199912404334 |
Quelle: | BISp |
Abstract des Autors
The effect of a single bout of mild exercise on glucose effectiveness (SG) and insulin sensitivity (SI) was studied in six young male subjects by using a minimal model. An intravenous glucose tolerance test was performed under two conditions as follows: 1) 25 min after a bout of exercise on a cycle ergometer at the lactate threshold level for 60 min (Ex) and 2) without any prior exercise (Con). Leg blood flow (LBF) was also measured by strain-gauge plethysmography simultaneously with blood sampling. SI did not significantly change after exercise (18.1+/-1.5 vs. 17.7+/-1.9 x 10**-5, min/pM), whereas SG significantly increased (0.016+/-0.002 vs. 0.025+/-0.002/min, P<0.01). The increased blood flow after exercise remained high during the time period for measurement of the glucose disappearance constant and may be a determinant of SG. The incremental lactate area under the curve until insulin loading was also significantly higher in Ex than in Con (2.6+/-0.9 vs. -3.5+/-1.5 mM/min, P<0.05). These results suggest that increased SG after mild exercise may be due, at least in part, to increased LBF and lactate production under a hyperglycemic state. Verf.-Referat