Immune responses to training: how critical is training volume?
Deutscher übersetzter Titel: | Reaktionen des Immunsystems auf koerperliches Training: wie entscheidend ist das Trainingsvolumen? |
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Autor: | Shore, S.; Shinkai, S.; Rhind, S.; Shephard, R.J. |
Erschienen in: | The Journal of sports medicine and physical fitness |
Veröffentlicht: | 39 (1999), 1, S. 1-11, Lit. |
Format: | Literatur (SPOLIT) |
Publikationstyp: | Zeitschriftenartikel |
Medienart: | Gedruckte Ressource |
Sprache: | Englisch |
ISSN: | 0022-4707, 1827-1928 |
Schlagworte: | |
Online Zugang: | |
Erfassungsnummer: | PU199905309126 |
Quelle: | BISp |
Abstract des Autors
Background: If the volume of training undertaken is sufficient to induce a negative energy balance, the anticipated benefit of an enhanced immune response may be reduced or lost. Methods: 33 sedentary but healthy male volunteers aged 19-29 years, recruited from the university community. A peak oxygen intake measurement (cycle ergometer) and a 60-min exercise challenge at 60% of aerobic power were performed before and after 12 wk of treatment. Total leukocytes, subsets, CD3+, CD4+, CD8+, CD16+, CD19+, and CD25+ counts (FACScan), cytolytic activity (51Cr release) and cell proliferation (PHA and PWM) were measured, with subjects assigned arbitrarily to one of three groups: light training (18 subjects, aerobic exercise at 70-85% HRmax 3 times/wk), moderate training (9 subjects, similar programme 4-5 times/wk) and control (6 subjects). Results: Groups were initially well-matched in physical and physiological terms. Training increased aerobic power (8% light, 21% moderate training), with a loss of body mass and fat in the moderate training group. Controls showed no changes. Resting CD16+ counts increased by 27% (light training) and CD16+ CD56+ counts by 21% (moderate training), with less post-exercise suppression of counts than at recruitment. Light training also decreased CD3+ and CD4+ counts without changing the CD4+/CD8+ ratio. Moderate training decreased resting CD19+ count.
Conclusions: From the viewpoint of immune function, the optimal training regimen is of low volume. Moderate training sufficient to induce a negative energy balance yields a smaller increase in numbers of non-MHC-restricted cytotoxic cells, and carries the negative consequence of diminished B cell counts. Verf.-Referat