Facteurs de la variation de la frequence cardiaque maximale : hypothese "enkephalinique"

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Deutscher übersetzter Titel:Faktoren der Veränderlichkeit der maximalen Herzfrequenz : die "Enkephalin-Hypothese"
Autor:Semmoum, Y.; Younes, A.; Coudert, J.
Erschienen in:Science & sports
Veröffentlicht:13 (1998), 6, S. 272-274, Lit.
Format: Literatur (SPOLIT)
Publikationstyp: Zeitschriftenartikel
Medienart: Gedruckte Ressource Elektronische Ressource (online)
Sprache:Französisch
ISSN:0765-1597, 1778-4131
DOI:10.1016/S0765-1597(99)80004-5
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Erfassungsnummer:PU199901306491
Quelle:BISp

Abstract des Autors

To try to explain the decrease in maximal heart rate under different situations (ie, chronic hypoxia, ageing, proteino-energetic malnutrition), cardiac concentration and flow of leucine-encephalin peptide in isolated and perfused hearts were studied in rats. The heart leucine-encephalin concentration which was 301+/-60 fmol/g before perfusion, increased up to 543+/-125 fmol/g after perfusion (1 h). The total release during perfusion was four times the initial concentration. Concerning the antagonism of leucine-encephalin on cardiotropic adrenergic effects on isolated cardiomyocytes, it is possible to propose this mechanism to explain totally or partially the decrease in maximal heart rate under particular situations. Verf.-Referat