Effects of exhaustive exercise on sarcoplasmic reticulum ATPase - comparison of short- and long-term exercise
Deutscher übersetzter Titel: | Auswirkungen erschoepfender koerperlicher Belastung auf die ATPase im sarkoplasmatischen Retikulum - Vergleich von lang- und kurzdauernder Belastung |
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Autor: | Inashima, S.; Yasuda, T.; Inamizu, A.; Wada, M.; Katsuta, S. |
Erschienen in: | Japanese journal of physical fitness and sports medicine |
Veröffentlicht: | 47 (1998), 1, S. 63-71, Lit. |
Format: | Literatur (SPOLIT) |
Publikationstyp: | Zeitschriftenartikel |
Medienart: | Gedruckte Ressource |
Sprache: | Japanisch |
ISSN: | 0039-906X, 1881-4751 |
Schlagworte: | |
Online Zugang: | |
Erfassungsnummer: | PU199806302290 |
Quelle: | BISp |
Abstract des Autors
Effects of short-term, high-intensity and long-term, moderate-intensity exercise on biochemically assessed sarcoplasmic reticulum (SR) ATPase protein were analyzed in muscle homogenates of the rat after treadmill runs to exhaustion (avg. time to exhaustion 2 min 48 sec and 1 h 29 min. respectively). The exercise-induced changes in SR Ca2+-ATPase activity were muscle type-specific. After short-term exercise, a decrease in the activity occurred in the soleus muscle and the superficial region of the vastus lateralis muscle whereas long-term exercise depressed the rate of ATP hydrolysis in the soleus muscle and the deep region of the vastus lateralis muscle. The concentration of fluorescein isothiocyanate, a competitor at the ATP-binding site, for 50% inhibition of SR Ca2+-ATPase activity fluctuated only in the soleus muscle subjected to short-term exercise; it was increased by 31%. This change occurring in the soleus muscle would elevate SR Ca2+-ATPase activity at a given concentration of ATP. The results presented here suggest that acute short-term exercise to exhaustion may exert a remarkably inhibitory factor on SR Ca2+-ATPase protein of slow-twitch muscle, which can overcome the positive effect probably arising from the phosphorylation of the phospholamban. Verf.-Referat