Using cine phase contrast magnetic resonance imaging to non-invasively study in vivo knee dynamics
Deutscher übersetzter Titel: | Anwendung der Cine-PC-MRI zur nicht invasiven Untersuchung der Kniegelenkdynamik in vivo |
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Autor: | Sheehan, F.T.; Zajac, F.E.; Drace, J.E. |
Erschienen in: | Journal of biomechanics |
Veröffentlicht: | 31 (1998), 1, S. 21-26, Lit. |
Format: | Literatur (SPOLIT) |
Publikationstyp: | Zeitschriftenartikel |
Medienart: | Gedruckte Ressource Elektronische Ressource (online) |
Sprache: | Englisch |
ISSN: | 0021-9290, 1873-2380 |
DOI: | 10.1016/S0021-9290(97)00109-7 |
Schlagworte: | |
Online Zugang: | |
Erfassungsnummer: | PU199805301910 |
Quelle: | BISp |
Abstract
We tested the accuracy and feasibility of using cine phase contrast magnetic resonance imaging (cine-PC MRI) to non-invasively measure three-dimensional, in vivo, skeletal velocity. Bone displacement was estimated by integrating the velocity measurements. Cine-PC MRI was originally developed to directly and non-invasively measure in vivo blood and heart velocity. Since no standard of reference exists for in vivo measurement of trabecular bone motion, a motion phantom (consisting of a series of paired gears that moved a sample box containing a human femoral bone sample) was built to assess the accuracy of tracking trabecular bone with cine-PC MRI. The in-plane, average absolute displacement errors were 0.55+/-0.38 and 0.36+/-0.27 mm in the x- and y-direction, respectively. Thus, estimates of bone position based on the integration of bone velocity measurements are affected little by the magnetic properties of bone (Majumdar and Genant (1995) Osteoporos International 5, 79-92). The velocity profiles of the patella, femur and tibia were measured in five healthy subjects during leg extensions. Extension was resisted by a 34 N weight. Subjects maintained a consistent motion rate (35+/-0.5 cycles/min) and motion artifacts were minimal. Our results indicate that patellar flexion lags knee flexion and the patella tilts laterally and then medially as the knee extends. We conclude cine-PC MRI is a promising technique for the non-invasive measurement of in vivo skeletal dynamics and, based on our previous work, muscular dynamics as well. Verf.-Referat