Use of ion trap (GC-MS-MS) mass spectrometry for detection and confirmation of anabolic substances at low concentration levels in doping analysis
Gespeichert in:
Deutscher übersetzter Titel: | Nutzen der Ionenfalle-(GC-MS-MS)-Massenspektrometrie fuer die dopinganalytische Entdeckung und Bestaetigung anaboler Substanzen auf niedrigster Konzentrationsebene |
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Autor: | Munoz-Guerra, J.; Carreras, D.; Soriano, C.; Rodriguez, C.; Rodriguez, A.F. |
Herausgeber: | Schänzer, Wilhelm; Geyer, Hans; Gotzmann, Andrea; Marek-Engelke, U. |
Erschienen in: | Recent advances in doping analysis (5) : Proceedings of the Manfred Donike Workshop ; 15th Cologne Workshop on Dope Analysis ; 23rd to 28th February 1997 |
Veröffentlicht: | Köln: Sport u. Buch Strauß (Verlag), 1998, 1998. S. 169-183, Lit., Lit. |
Format: | Literatur (SPOLIT) |
Publikationstyp: | Sammelwerksbeitrag |
Medienart: | Gedruckte Ressource |
Sprache: | Englisch |
ISBN: | 3890010164 |
Schlagworte: | |
Online Zugang: | |
Erfassungsnummer: | PU199805301842 |
Quelle: | BISp |
Abstract des Autors
These results prove that the use of the GC-MS-MS ion trap system is effective in the analysis of complex matrices such as urine. This technique has been shown to be a powerful tool for the detection and confirmation of anabolic substances at low concentrations in urine samples proceeding from sporting competitions. The analytical method used was highly sensitive, easy to optimize, time saving and allows to confirm anabolic substances at concentrations levels at which injecting by Single Ion Monitoring it is only possible detection. Therefore GC-MS-MS is a good complement to the SIM or similar GC-MS methods for analyzing anabolic compounds. Verf.-Referat