Respiratory effort sensation during exercise with induced expiratory-flow limitation in healthy humans
Deutscher übersetzter Titel: | Respiratorische Anstrengungsempfindung unter koerperlicher Belastung mit kuenstlich eingeschraenkter Exspiration beim Menschen |
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Autor: | Kayser, B.; Sliwinski, P.; Yan, S.; Tobiasz, M.; Macklem, P.T. |
Erschienen in: | Journal of applied physiology |
Veröffentlicht: | 83 (1997), 3, S. 936-947, Lit. |
Format: | Literatur (SPOLIT) |
Publikationstyp: | Zeitschriftenartikel |
Medienart: | Gedruckte Ressource |
Sprache: | Englisch |
ISSN: | 8750-7587, 0021-8987, 0161-7567, 1522-1601 |
Schlagworte: | |
Online Zugang: | |
Erfassungsnummer: | PU199709207191 |
Quelle: | BISp |
Abstract des Autors
Nine healthy subjects (age 31+/-4 yr) exercised with and without expiratory-flow limitation (maximal flow ca. 1 l/s). We monitored flow, end-tidal PCO2, esophageal (Pes) and gastric pressures, changes in end-expiratory lung volume, and perception (sensation) of difficulty in breathing. Subjects cycled at increasing intensity (+25 W/30 s) until symptom limitation. During the flow-limited run, exercise performance was limited in all subjects by maximum sensation. Sensation was equally determined by inspiratory and expiratory pressure changes. In both runs, 90% of the variance in sensation could be explained by the Pes swings (difference between peak inspiratory and peak expiratory Pes). End-tidal PCO2 did not explain any variance in sensation in the control run and added only 3% to the explained variance in the flow-limited run. We conclude that in healthy subjects, during normal as well as expiratory flow-limited exercise, the pleural pressure generation of the expiratory muscles is equally related to the perception of difficulty in breathing as that of the inspiratory muscles. Verf.-Referat