Metabolic adaptations to endurance training monitored by blood lactate concentration in male rats

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Bibliographic Details
Title translated into German:Stoffwechselanpassungen an Ausdauertraining, nachgewiesen anhand der Blutlaktatkonzentration bei maennlichen Ratten
Author:Zhang, Nan; Terao, Tamotsu; Nakano, Shoichi
Published in:Japanese journal of physical fitness and sports medicine
Published:44 (1995), 1 , S. 127-136, Lit.
Format: Publications (Database SPOLIT)
Publication Type: Journal article
Media type: Print resource
Online Access:
Identification number:PU199603106619

Author's abstract

We studied the effects of 8 weeks of endurance training on the metabolism in rats. Different treadmill speeds, which corresponded to 2 mM and 4 mM blood lactate concentrations, were used to vary the intensity of the endurance training. After 8 weeks of training, blood lactate concentrations had decreased whereas beta-hydroxyacyl-CoA dehydrogenase activity had increased. Citrate synthase activity in the m. extensor digitorum longus (EDL), and m. tibialis anterior (TA) of rats trained at the 4 mM level was higher than in rats trained at the 2 mM level and in control rats. In addition, muscle glycogen content in the hindlimb was higher and muscle TG content in the m. soleus (SOL) was lower in trained rats. These results suggest that training at 4 mM level significantly increases muscle mitochondrial oxidative capacity, and fatty acids are utilized as an energy source regardless of exercise intensity at least in the 2 to 4 mM intensity range. We conclude that an intensity of 4 mM is a useful level with which to elucidate the various adaptations to endurance training. Verf.-Referat