Abstract des Autors

Adult male albino rats were randomly assigned to three groups. Rats in group A swam to exhaustion. Rats in group B swam to death. Rats in group C had a rest for 24 hours after their swimming to exhaustion. The ultrastructures of left ventricular muscle in all the three groups were observed by electron microscopy. Meanwhile the Numerical Density (Nv), the Average Volume (V), the Shape Coefficient (I) of mitochondria were also measured. Comparing with the corresponding control group, the V of mitochondria in group A and B increased significantly, the Nv of mitochondria in group B decreased significantly, the I of mitochondria in group B increased significantly, the V, Nv, and I of mitochondria in group C had no significant difference. The results indicated that the myocardium mitochondria in exhaustive and overloaded rats were swollen, and the number of mitochondria in overloaded rats decreased and the shape of them changed obviously. It suggested that the myocardial injury could be induced by exhaustive swimming. However this kind of damagement may recover after a period of resting. The serious myocardial injury can be induced by overloaded swimming. Verf.-Referat