Abstract

During high-intensity, short-duration exercise, muscle AMP ist deaminated to form IMP and ammonia (NH3) by the enzyme AMP deaminase. Increased AMP deamination occurs because the rate of ATP hydrolysis exceeds ATP resynthesis, and this results in increased muscle NH3 concentrations which closely match decreases in ATP concentration. Since NH3 may diffuse across the sarcolemma into the circulation, the increase in plasma NH3 concentration with intense exercise may reflect the state of energy balance within active muscle. The effect of sprint training on muscle or blood NH3 has not yet been determined, although it has been reported that post-exercise ATP levels are not different after sprint training. The present study was undertaken to examine the effect of sprint training on post-exercise plasma NH3 accumulation. Verf.-Referat