Hypothalamic-pituitary-testicular axis function in endurance-trained males
Gespeichert in:
Deutscher übersetzter Titel: | Funktion der Hypothalamus-Hypophysen-Testes-Achse bei ausdauertrainierten Maennern |
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Autor: | Hackney, Anthony Carl; Sinning, W.E.; Bruot, B.C. |
Erschienen in: | International journal of sports medicine |
Veröffentlicht: | 11 (1990), 4, S. 298-303, Lit. |
Format: | Literatur (SPOLIT) |
Publikationstyp: | Zeitschriftenartikel |
Medienart: | Gedruckte Ressource Elektronische Ressource (online) |
Sprache: | Englisch |
ISSN: | 0172-4622, 1439-3964 |
DOI: | 10.1055/s-2007-1024811 |
Schlagworte: | |
Online Zugang: | |
Erfassungsnummer: | PU199201046363 |
Quelle: | BISp |
id |
PU199201046363 |
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bisp-collection |
db |
format |
Literatur |
last_indexed |
2021-01-06T08:05:30Z |
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2003-12-30T14:19:13Z |
publication_source |
BISp |
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Zeitschriftenartikel |
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JO00000000664 |
hierarchy_parent_id |
JOI199000040000664 |
hierarchy_top_title |
International journal of sports medicine |
hierarchy_parent_title |
International journal of sports medicine, 1990, 4 |
is_hierarchy_id |
PU199201046363 |
is_hierarchy_title |
Hypothalamic-pituitary-testicular axis function in endurance-trained males |
hierarchy_sequence |
0298 |
recordtype |
bisparticle |
publishDate |
1990 |
publishDate_facet |
1990 |
language |
eng |
title |
Hypothalamic-pituitary-testicular axis function in endurance-trained males |
spellingShingle |
Hypothalamic-pituitary-testicular axis function in endurance-trained males Ausdauersport Ausdauertraining Endokrinium Gonadotropin Hormonkonzentration Hypophysenhormon Kortisol LH LTH Mann Sexualhormon Sportmedizin Testosteron Trainingswirkung Östradiol |
title_sort |
hypothalamicpituitarytesticular axis function in endurancetrained males |
title_short |
Hypothalamic-pituitary-testicular axis function in endurance-trained males |
title_alt |
Funktion der Hypothalamus-Hypophysen-Testes-Achse bei ausdauertrainierten Maennern |
title_alt_lang |
deu |
media_type |
Gedruckte Ressource Elektronische Ressource (online) |
city |
Stuttgart |
abstract |
The hypothalamic-pituitary-testicular (H-P-T) axis was evaluated in groups of endurance-trained (TRG) and untrained (UNT) males. Each group was subjected to: 1) a 4-h resting hormonal profile <testosterone (T), free-testosterone (FT), estradiol (E2), luteinizing hormone (LH), prolactin (PRL), and cortisol (C)>, 2) a dopamine antagonist (DA) challenge to the pituitary-testes, and 3) a gonadotropin-releasing hormone (GnRH) challenge to the pituitary-testes. Compared to UNT, the TRG resting T (4.8+/-0.7 vs 7.1+/-1.2 ng/ml) and PRL (3.3+/-1.4 vs 7.0+/-2.3 ng/ml) were lower while LH was elevated (15.0+/-1.8 vs 11.8+/-1.5 mIU/ml). The DA challenge produced a greater integrated PRL response in the TRG (2962.7+/-265.1 ng/ml/min) than in the UNT (1735.3+/-282.0 ng/ml/min). No significant changes were observed in T following the DA-induced PRL rise. The TRG had a blunted LH response (817.2+/-111.6 mIU ml/min) following the GnRH injection as compared to the UNT (1493.7+/-213.4 mIU/ml/min). T levels were significantly increased in both groups by the LH rise after the GnRH challenge (TRG = 9.9+/-5.0; UNT = 8.6+/-9.9, respectively), but no significant between group differences were observed. Results suggest endurance training produces an enhanced PRL and attenuated LH release by the pituitary. Whether these alterations may have a direct effect on the functional status of the H-P-T axis, resulting in the suppressed resting levels of T in the TRG, remains uncertain. Verf.-Referat |
abstract_lang |
eng |
abstract_type |
abstract |
author2 |
Hackney, Anthony Carl Sinning, W.E. Bruot, B.C. |
author_facet |
Hackney, Anthony Carl Sinning, W.E. Bruot, B.C. |
author2-role |
Autor Autor Autor |
author2-authorityid |
P76765 |
author_author_facet |
Hackney, Anthony Carl Sinning, W.E. Bruot, B.C. |
author2-synonym |
|
author2_hierarchy_facet |
0/Autor/ 1/Autor/Hackney, Anthony Carl/ 0/Autor/ 1/Autor/Sinning, W.E./ 0/Autor/ 1/Autor/Bruot, B.C./ |
doi |
10.1055/s-2007-1024811 |
spelling |
10.1055/s-2007-1024811 0172-4622 1439-3964 IJSMD 603122-5 Ausdauersport Ausdauertraining Endokrinium Gonadotropin Hormonkonzentration Hypophysenhormon Kortisol LH LTH Mann Sexualhormon Sportmedizin Testosteron Trainingswirkung Östradiol cortisol endocrinium endurance sport endurance training estradiol gonadotropin hormone concentration LH LTH man pituitary hormone sexual hormone sports medicine testosterone training effect Ausdauersportler Ausdauerschulung Dauertraining Trainingseffekt Trainingserfolg Cortisol Hormonspiegel Männerklasse Medizin Geschichte der Medizin Untersuchung, sportmedizinische Wasserdampf luteinizing hormone luteotrophic hormone endocrine system Hypothalamic-pituitary-testicular axis function in endurance-trained males PU199201046363 199201046363 |
url |
https://dx.doi.org/10.1055/s-2007-1024811 |
url-type |
fulltext |
url-free |
1 |
free_access |
1 |
issn |
0172-4622 1439-3964 |
coden |
IJSMD |
zdb |
603122-5 |
location_hierarchy_facet |
0/Deutschland/ 1/Deutschland/Baden-Württemberg/ |
topic |
Ausdauersport Ausdauertraining Endokrinium Gonadotropin Hormonkonzentration Hypophysenhormon Kortisol LH LTH Mann Sexualhormon Sportmedizin Testosteron Trainingswirkung Östradiol |
topic_facet |
Ausdauersport Ausdauertraining Endokrinium Gonadotropin Hormonkonzentration Hypophysenhormon Kortisol LH LTH Mann Sexualhormon Sportmedizin Testosteron Trainingswirkung Östradiol |
topic_en |
cortisol endocrinium endurance sport endurance training estradiol gonadotropin hormone concentration LH LTH man pituitary hormone sexual hormone sports medicine testosterone training effect |
topic_en_facet |
cortisol endocrinium endurance sport endurance training estradiol gonadotropin hormone concentration LH LTH man pituitary hormone sexual hormone sports medicine testosterone training effect |
synonym |
Ausdauersportler Ausdauerschulung Dauertraining Trainingseffekt Trainingserfolg Cortisol Hormonspiegel Männerklasse Medizin Geschichte der Medizin Untersuchung, sportmedizinische Wasserdampf |
synonym_en |
luteinizing hormone luteotrophic hormone endocrine system |
journal_facet |
International journal of sports medicine |
container_title |
International journal of sports medicine |
container_volume |
11 |
container_issue |
4 |
container_start_page |
S. 298-303 |
has_references |
1 |
institution |
BISp |
journal_fac |
JO00000000664 |
journal_year |
1990 |
journal_issue |
4 |
_version_ |
1791519094774693888 |
score |
13,558404 |