Hypothalamic-pituitary-testicular axis function in endurance-trained males

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Deutscher übersetzter Titel:Funktion der Hypothalamus-Hypophysen-Testes-Achse bei ausdauertrainierten Maennern
Autor:Hackney, Anthony Carl; Sinning, W.E.; Bruot, B.C.
Erschienen in:International journal of sports medicine
Veröffentlicht:11 (1990), 4, S. 298-303, Lit.
Format: Literatur (SPOLIT)
Publikationstyp: Zeitschriftenartikel
Medienart: Gedruckte Ressource Elektronische Ressource (online)
Sprache:Englisch
ISSN:0172-4622, 1439-3964
DOI:10.1055/s-2007-1024811
Schlagworte:
LH
LTH
Online Zugang:
Erfassungsnummer:PU199201046363
Quelle:BISp
id PU199201046363
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last_indexed 2021-01-06T08:05:30Z
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hierarchy_top_id JO00000000664
hierarchy_parent_id JOI199000040000664
hierarchy_top_title International journal of sports medicine
hierarchy_parent_title International journal of sports medicine, 1990, 4
is_hierarchy_id PU199201046363
is_hierarchy_title Hypothalamic-pituitary-testicular axis function in endurance-trained males
hierarchy_sequence 0298
recordtype bisparticle
publishDate 1990
publishDate_facet 1990
language eng
title Hypothalamic-pituitary-testicular axis function in endurance-trained males
spellingShingle Hypothalamic-pituitary-testicular axis function in endurance-trained males
Ausdauersport
Ausdauertraining
Endokrinium
Gonadotropin
Hormonkonzentration
Hypophysenhormon
Kortisol
LH
LTH
Mann
Sexualhormon
Sportmedizin
Testosteron
Trainingswirkung
Östradiol
title_sort hypothalamicpituitarytesticular axis function in endurancetrained males
title_short Hypothalamic-pituitary-testicular axis function in endurance-trained males
title_alt Funktion der Hypothalamus-Hypophysen-Testes-Achse bei ausdauertrainierten Maennern
title_alt_lang deu
media_type Gedruckte Ressource
Elektronische Ressource (online)
city Stuttgart
abstract The hypothalamic-pituitary-testicular (H-P-T) axis was evaluated in groups of endurance-trained (TRG) and untrained (UNT) males. Each group was subjected to: 1) a 4-h resting hormonal profile <testosterone (T), free-testosterone (FT), estradiol (E2), luteinizing hormone (LH), prolactin (PRL), and cortisol (C)>, 2) a dopamine antagonist (DA) challenge to the pituitary-testes, and 3) a gonadotropin-releasing hormone (GnRH) challenge to the pituitary-testes. Compared to UNT, the TRG resting T (4.8+/-0.7 vs 7.1+/-1.2 ng/ml) and PRL (3.3+/-1.4 vs 7.0+/-2.3 ng/ml) were lower while LH was elevated (15.0+/-1.8 vs 11.8+/-1.5 mIU/ml). The DA challenge produced a greater integrated PRL response in the TRG (2962.7+/-265.1 ng/ml/min) than in the UNT (1735.3+/-282.0 ng/ml/min). No significant changes were observed in T following the DA-induced PRL rise. The TRG had a blunted LH response (817.2+/-111.6 mIU ml/min) following the GnRH injection as compared to the UNT (1493.7+/-213.4 mIU/ml/min). T levels were significantly increased in both groups by the LH rise after the GnRH challenge (TRG = 9.9+/-5.0; UNT = 8.6+/-9.9, respectively), but no significant between group differences were observed. Results suggest endurance training produces an enhanced PRL and attenuated LH release by the pituitary. Whether these alterations may have a direct effect on the functional status of the H-P-T axis, resulting in the suppressed resting levels of T in the TRG, remains uncertain. Verf.-Referat
abstract_lang eng
abstract_type abstract
author2 Hackney, Anthony Carl
Sinning, W.E.
Bruot, B.C.
author_facet Hackney, Anthony Carl
Sinning, W.E.
Bruot, B.C.
author2-role Autor
Autor
Autor
author2-authorityid P76765


author_author_facet Hackney, Anthony Carl
Sinning, W.E.
Bruot, B.C.
author2-synonym


author2_hierarchy_facet 0/Autor/
1/Autor/Hackney, Anthony Carl/
0/Autor/
1/Autor/Sinning, W.E./
0/Autor/
1/Autor/Bruot, B.C./
doi 10.1055/s-2007-1024811
spelling 10.1055/s-2007-1024811
0172-4622
1439-3964
IJSMD
603122-5
Ausdauersport
Ausdauertraining
Endokrinium
Gonadotropin
Hormonkonzentration
Hypophysenhormon
Kortisol
LH
LTH
Mann
Sexualhormon
Sportmedizin
Testosteron
Trainingswirkung
Östradiol
cortisol
endocrinium
endurance sport
endurance training
estradiol
gonadotropin
hormone concentration
LH
LTH
man
pituitary hormone
sexual hormone
sports medicine
testosterone
training effect
Ausdauersportler
Ausdauerschulung
Dauertraining
Trainingseffekt
Trainingserfolg
Cortisol
Hormonspiegel
Männerklasse
Medizin
Geschichte der Medizin
Untersuchung, sportmedizinische
Wasserdampf
luteinizing hormone
luteotrophic hormone
endocrine system
Hypothalamic-pituitary-testicular axis function in endurance-trained males
PU199201046363
199201046363
url https://dx.doi.org/10.1055/s-2007-1024811
url-type fulltext
url-free 1
free_access 1
issn 0172-4622
1439-3964
coden IJSMD
zdb 603122-5
location_hierarchy_facet 0/Deutschland/
1/Deutschland/Baden-Württemberg/
topic Ausdauersport
Ausdauertraining
Endokrinium
Gonadotropin
Hormonkonzentration
Hypophysenhormon
Kortisol
LH
LTH
Mann
Sexualhormon
Sportmedizin
Testosteron
Trainingswirkung
Östradiol
topic_facet Ausdauersport
Ausdauertraining
Endokrinium
Gonadotropin
Hormonkonzentration
Hypophysenhormon
Kortisol
LH
LTH
Mann
Sexualhormon
Sportmedizin
Testosteron
Trainingswirkung
Östradiol
topic_en cortisol
endocrinium
endurance sport
endurance training
estradiol
gonadotropin
hormone concentration
LH
LTH
man
pituitary hormone
sexual hormone
sports medicine
testosterone
training effect
topic_en_facet cortisol
endocrinium
endurance sport
endurance training
estradiol
gonadotropin
hormone concentration
LH
LTH
man
pituitary hormone
sexual hormone
sports medicine
testosterone
training effect
synonym Ausdauersportler
Ausdauerschulung
Dauertraining
Trainingseffekt
Trainingserfolg
Cortisol
Hormonspiegel
Männerklasse
Medizin
Geschichte der Medizin
Untersuchung, sportmedizinische
Wasserdampf
synonym_en luteinizing hormone
luteotrophic hormone
endocrine system
journal_facet International journal of sports medicine
container_title International journal of sports medicine
container_volume 11
container_issue 4
container_start_page S. 298-303
has_references 1
institution BISp
journal_fac JO00000000664
journal_year 1990
journal_issue 4
_version_ 1791519094774693888
score 13,558404