Muscle malonyl-CoA decreases during exercise
Gespeichert in:
| Deutscher übersetzter Titel: | Der Gehalt des Muskels an Malonyl-CoA vermindert sich bei Muskelarbeit |
|---|---|
| Autor: | Winder, W.W.; Arogyasami, J.; Barton, R.J.; Elayan, I.M.; Vehrs, P.R. |
| Erschienen in: | Journal of applied physiology |
| Veröffentlicht: | 67 (1989), 6, S. 2230-2233, Lit. |
| Format: | Literatur (SPOLIT) |
| Publikationstyp: | Zeitschriftenartikel |
| Medienart: | Gedruckte Ressource |
| Sprache: | Englisch |
| ISSN: | 8750-7587, 0021-8987, 0161-7567, 1522-1601 |
| Schlagworte: | |
| Online Zugang: | |
| Erfassungsnummer: | PU199003042937 |
| Quelle: | BISp |
| id |
PU199003042937 |
|---|---|
| bisp-collection |
db |
| format |
Literatur |
| last_indexed |
2009-04-28T09:52:40Z |
| first_indexed |
2003-12-30T14:11:13Z |
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BISp |
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Zeitschriftenartikel |
| hierarchy_top_id |
JO00000000714 |
| hierarchy_parent_id |
JOI198900060000714 |
| hierarchy_top_title |
Journal of applied physiology |
| hierarchy_parent_title |
Journal of applied physiology, 1989, 6 |
| is_hierarchy_id |
PU199003042937 |
| is_hierarchy_title |
Muscle malonyl-CoA decreases during exercise |
| hierarchy_sequence |
2230 |
| recordtype |
bisparticle |
| publishDate |
1989 |
| publishDate_facet |
1989 |
| language |
eng |
| title |
Muscle malonyl-CoA decreases during exercise |
| spellingShingle |
Muscle malonyl-CoA decreases during exercise Energiestoffwechsel Fettsäuremobilisation Fettsäurestoffwechsel Muskelarbeit Muskelstoffwechsel Sportmedizin |
| title_sort |
muscle malonylcoa decreases during exercise |
| title_short |
Muscle malonyl-CoA decreases during exercise |
| title_alt |
Der Gehalt des Muskels an Malonyl-CoA vermindert sich bei Muskelarbeit |
| title_alt_lang |
deu |
| media_type |
Gedruckte Ressource |
| city |
Bethesda (Maryld.) |
| abstract |
Malonyl-CoA, the inhibitor of carnitine acyltransferase I, is an important regulator of fatty acid oxidation and ketogenesis in the liver. Muscle carnitine acyltransferase I has previously been reported to be more sensitive to malonyl-CoA inhibition than is liver carnitine acyltransferase I. Fluctuations in malonyl-CoA concentration may therefore be important in regulating the rate of fatty acid oxidation in muscle during exercise. Male rats were anesthetized (pentobarbital via venous catheters) at rest or after 30 min of treadmill exercise (21 m/min, 15 grade). The gastrocnemius/plantaris muscles were frozen at liquid N2 temperature. Muscle malonyl-CoA decreased from 1.66 +/- 0.17 to 0.60 +/- 0.05 nmol/g during the exercise. This change was accompanied by a 31 increase in cAMP in the muscle. The decline in malonyl-CoA occurred before muscle glycogen depletion and before onset of hypoglycemia. Plasma catecholamines, corticosterone, and free fatty acids were all significantly increased during the exercise. This exercise-induced decrease in malonyl-CoA may be important for allowing the increase in muscle fatty acid oxidation during exercise. Verf.-Referat |
| abstract_lang |
eng |
| abstract_type |
abstract |
| author2 |
Winder, W.W. Arogyasami, J. Barton, R.J. Elayan, I.M. Vehrs, P.R. |
| author_facet |
Winder, W.W. Arogyasami, J. Barton, R.J. Elayan, I.M. Vehrs, P.R. |
| author2-role |
Autor Autor Autor Autor Autor |
| author2-authorityid |
|
| author_author_facet |
Winder, W.W. Arogyasami, J. Barton, R.J. Elayan, I.M. Vehrs, P.R. |
| author2-synonym |
|
| author2_hierarchy_facet |
0/Autor/ 1/Autor/Winder, W.W./ 0/Autor/ 1/Autor/Arogyasami, J./ 0/Autor/ 1/Autor/Barton, R.J./ 0/Autor/ 1/Autor/Elayan, I.M./ 0/Autor/ 1/Autor/Vehrs, P.R./ |
| issn |
8750-7587 0021-8987 0161-7567 1522-1601 |
| spelling |
8750-7587 0021-8987 0161-7567 1522-1601 JAPYA 219139-8 Energiestoffwechsel Fettsäuremobilisation Fettsäurestoffwechsel Muskelarbeit Muskelstoffwechsel Sportmedizin energy metabolism fatty acid metabolism fatty acid mobilization muscle metabolism muscle work sports medicine Energiehaushalt Medizin Geschichte der Medizin Untersuchung, sportmedizinische Wasserdampf Muscle malonyl-CoA decreases during exercise PU199003042937 199003042937 |
| coden |
JAPYA |
| zdb |
219139-8 |
| location_hierarchy_facet |
0/USA/ 1/USA/Maryland/ |
| topic |
Energiestoffwechsel Fettsäuremobilisation Fettsäurestoffwechsel Muskelarbeit Muskelstoffwechsel Sportmedizin |
| topic_facet |
Energiestoffwechsel Fettsäuremobilisation Fettsäurestoffwechsel Muskelarbeit Muskelstoffwechsel Sportmedizin |
| topic_en |
energy metabolism fatty acid metabolism fatty acid mobilization muscle metabolism muscle work sports medicine |
| topic_en_facet |
energy metabolism fatty acid metabolism fatty acid mobilization muscle metabolism muscle work sports medicine |
| synonym |
Energiehaushalt Medizin Geschichte der Medizin Untersuchung, sportmedizinische Wasserdampf |
| journal_facet |
Journal of applied physiology |
| container_title |
Journal of applied physiology |
| container_volume |
67 |
| container_issue |
6 |
| container_start_page |
S. 2230-2233 |
| has_references |
1 |
| institution |
BISp |
| journal_fac |
JO00000000714 |
| journal_year |
1989 |
| journal_issue |
6 |
| _version_ |
1810943692089851904 |
| score |
13,28347 |