Role of oxygen in the production of human decompression sickness

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Bibliographische Detailangaben
Deutscher übersetzter Titel:Rolle des Sauerstoffs bei der Entstehung der Dekompressionskrankheit beim Menschen
Autor:Weathersby, P.K.; Hart, B.L.; Flynn, E.T.; Walker, W.F.
Erschienen in:Journal of applied physiology
Veröffentlicht:63 (1987), 6, S. 2380-2387, Lit.
Format: Literatur (SPOLIT)
Publikationstyp: Zeitschriftenartikel
Medienart: Gedruckte Ressource
Sprache:Englisch
ISSN:8750-7587, 0021-8987, 0161-7567, 1522-1601
Schlagworte:
Gas
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Erfassungsnummer:PU198807012532
Quelle:BISp

Abstract

In the calculation of decompression schedules, it is commonly assumed that only the inert gas needs to be considered; all inspired O2 is ignored. Animal experiments have shown that high O2 can increase risk of serious decompression sickness (DCS). A trial was performed to assess the relative risks of O2 and N2 in human no-decompression dives. Controlled dives (477) of 30- to 240-min duration were performed with subjects breathing mixtures with low (0.21-0.38 ATA) or high (1.0-1.5 ATA) PO2. Depths were chosen by a sequential dose-response format. Only 11 cases of DCS and 18 cases of marginal symptoms were recorded despite exceeding the presently accepted no-decompression limits by >20. Analysis by maximum likelihood showed a shallow dose-response curve for increasing depth. O2 was estimated to have zero influence on DCS risk, although data variability still allows a slight chance that O2 could be 40 as effective as N2 in producing a risk of DCS. Consideration of only inert gases is thus justified in calculating human decompression tables. Verf.-Referat