The effect of anaerobic-type exercise training on serum and hepatic cholesterol metabolism in rats

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Deutscher übersetzter Titel:Die Auswirkungen anaerober Trainingsbelastungen auf den Serum- und Leber-Cholesterolstoffwechsel von Ratten
Autor:Abe, Takashi; Asami, Toshio
Erschienen in:The Proceedings of the Department of Sports Sciences, College of Arts and Sciences, University of Tokyo
Veröffentlicht:1988, 22, S. 23-30, Lit.
Format: Literatur (SPOLIT)
Publikationstyp: Zeitschriftenartikel
Medienart: Gedruckte Ressource
Sprache:Englisch
ISSN:0495-7865
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Erfassungsnummer:PU198807009828
Quelle:BISp

Abstract

In order to examine the effect of anaerobic-type exercise training on serum HDL cholesterol level and hepatic cholesterol metabolism, male Wistar rats were randomly divided into a sedentary control (n=7) and a jumping group (n=6). The experimental animals were forced to jump to a hight of 30 cm wearing a vest loaded with up to 50 of their body weight, 50-70 time/day, one bout at every 2-3 sec., 5 days/wk for 16 wks. The jumping rats showed significantly lower levels of serum total and HDL cholesterol than the control. The serum LCAT activity was decreased more in the jumping rats than in the control. The hepatic microsomal HMG-CoA reductase activity in the jumping rats was significantly higher compared with those of the sedentary group. Since the hepatic cholesterol synthesis and degradation were increased by jumping training, the changes in serum lipoprotein cholesterol levels observed following exercise seemed to be caused by extrahepatic mechanisms. Verf.-Referat